Periodic Reporting for period 1 - ComTransTrep (Comparative transcriptomics of phylogenetically selected pathogenic treponemes cultivated in vitro under different conditions: First insight to the expression changes linked with genomic variants)

Despite over a century of scientific research on Treponema pallidum subsp. pallidum (TPA), the infectious agent of syphilis, our understanding of its biology is very limited. This is mainly because, in general, pathogenic treponemes are considered uncultivable bacteria, and...