Periodic Reporting for period 1 - BiCyHePepDi (Bicyclic hetero peptidimer - a novel molecule format for therapeutic peptides)

The development of a novel molecule format, referred to as “bicyclic hetero peptidimer” (Figure 1), as a new therapeutic molecule format is the first objective in this project. By combination of a moderate active inhibitor of FXIIa with a FXII binding peptide, we...