Scientific article of ESR2 on Methods and Design Rules developed for Continuous Configurations of Crystallization-based Chiral Synthesis

Development of Continuous Crystallization-enabled Chiral Synthesis Processes. This part will be led by JtH at USTRATH with the involvement of ESR2 at USTRATH (experiments) and ESR4 at ETH (process modelling). There is a strong connection with ESR5 at RUN and ESR6 at SYNCOM working on batchwise crystallization-enabled chiral synthesis. Recently, it was shown that a combination of an aselective reversible reaction with Viedma Ripening leads to a chiral synthesis route [8]. ESR2 will transfer this new batchwise chiral synthesis route into continuous configurations. The partner SYNCOM is willing, during the industrial secondment, to facilitate the synthesis of substantial amount of raw material needed to perform long term continuous experiments.