Biochemical characterization of the Scrib polarity complex

Biochemical characterization of the Scrib polarity complex will involve a) identification of new partners of the mammalian polarity protein Scrib, b) biochemical characterization of the Scrib polarity complex in migrating cells and polarized epithelial cells, and c) characterization of the polarity function of Scrib partners in migrating cells and polarized epithelial cells.