Mechanochemical model of PAR polarity patterning

1. Development of a mechanochemical model of PAR polarity patterning will involve a) simultaneous and complete midplane concentration and flowfields of markers of polarity and the actomyosin cortex under wild type and RNAi conditions, b) Identication of which markers of polarity control what activities of the cellular cytoskeleton, c) Development of a quantitative and predictive description of PAR polarity as a process of mechanochemical patterning formation in a regulated thin film active fluid.