Pyrimidine de novo synthesis inhibition selectively blocks effector but not memory T cell development

Summary

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Authors: Stefanie Scherer, Susanne G Oberle, Kristiyan Kanev, Ann-Katrin Gerullis, Ming Wu, Gustavo P de Almeida, Daniel J Puleston, Francesc Baixauli, Lilian Aly, Alessandro Greco, Tamar Nizharadze, Nils B Becker, Madlaina V Hoesslin, Lara V Donhauser, Jacqueline Berner, Talyn Chu, Hayley A McNamara, Zeynep Esencan, Patrick Roelli, Christine Wurmser, Ingo Kleiter, Maria J G T Vehreschild, Christoph A Maye

Journal title: Nature Communications

Journal number: 24(3)

Journal publisher: Nature Publishing Group

Published year: 2023

Published pages: 501-515

DOI identifier: 10.1038/s41590-023-01436-x

ISSN: 1529-2908