Periodic Reporting for period 1 - GUTPOLAR (Membrane trafficking as a link between cell polarity and intestinal absorptive function: from C. elegans to mammalian miniguts)

Intestinal absorption of nutrients from the diet relies on both the strong polarity of the intestinal epithelial cells and the array of microvilli forming an absorptive brush border (BB) at their apical pole. Previous studies suggested that membrane trafficking plays a major...