Oncogenic mutations at the EGFR ectodomain structurally converge to remove a steric hindrance on a kinase-coupled cryptic epitope

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Authors: Laura Orellana, Amy H. Thorne, Rafael Lema, Johan Gustavsson, Alison D. Parisian, Adam Hospital, Tiago N. Cordeiro, Pau Bernadó, Andrew M. Scott, Isabelle Brun-Heath, Erik Lindahl, Webster K. Cavenee, Frank B. Furnari, Modesto Orozco

Journal title: Proceedings of the National Academy of Sciences

Journal number: 116/20

Journal publisher: National Academy of Sciences

Published year: 2019

Published pages: 10009-10018

DOI identifier: 10.1073/pnas.1821442116

ISSN: 0027-8424