Cavity filling mutations at the thyroxine-binding site dramatically increase transthyretin stability and prevent its aggregation

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Authors: Ricardo Sant’Anna, Maria Rosário Almeida, Nathalia Varejāo, Pablo Gallego, Sebastian Esperante, Priscila Ferreira, Alda Pereira-Henriques, Fernando L. Palhano, Mamede de Carvalho, Debora Foguel, David Reverter, Maria João Saraiva, Salvador Ventura

Journal title: Scientific Reports

Journal number: 7/1

Journal publisher: Nature Publishing Group

Published year: 2017

DOI identifier: 10.1038/srep44709

ISSN: 2045-2322