D1.5 Full integration of atlas services, models and validation including DEMO3 of Showcases 1 and 2

Software integrating workflows of EBRAINS services (atlas, knowledge graph, HIP) and TVB will be available making full use of the brain reference framework, comprising the release of a variety of models of human brain networks acknowledging population variability, assessment of reliability, and normative data on model parameters in relation to demographic, lifestyle, and cognitive data of large cohorts. Integrated workflows will be available to create personalised brain network models in small detailed cohorts, enabling mutual prediction of brain states in different healthy (rest, cognitive tasks) and diseased conditions. The software will allow demonstrations of the showcases comprising the evaluation of predictive power of epileptic patient brain models, validated on large retrospective cohort (>100 patients), ready for clinical trial testing; as well as demonstrations of sampling of individual degeneracy from empirical functional resting-state imaging data and reconstruction of virtual brain model variability.