Optimizing the enzymatic release of MMAE from isoDGR-based small molecule drug conjugate by incorporation of a GPLG-PABC enzymatically cleavable linker

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Authors: Marco Zambra; Ivan Ranđelović; Francesco Talarico; Adina Borbély; Laura Svajda; Laura Svajda; József Tóvári; Gábor Mező; Gábor Mező; Lizeth Bodero; Sveva Colombo; Sveva Colombo; Federico Arrigoni; Elettra Fasola; Silvia Gazzola; Umberto Piarulli

Journal title: Frontiers in Pharmacology, Vol 14 (2023)

Journal number: 14

Journal publisher: Frontiers Media S.A.

Published year: 2023

Published pages: 1215694

DOI identifier: 10.3389/fphar.2023.1215694

ISSN: 1663-9812