Focused Screening Identifies Different Sensitivities of Human TET Oxygenases to the Oncometabolite 2-Hydroxyglutarate

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Authors: Roman Belle; Hilal Saraç; Eidarus Salah; Bhaskar Bhushan; Aleksandra Szykowska; Grace Roper; Anthony Tumber; Skirmantas Kriaucionis; Nicola Burgess-Brown; Christopher J. Schofield; Tom Brown; Akane Kawamura

Journal title: Journal of Medicinal Chemistry

Journal number: 67 (6)

Journal publisher: American Chemical Society

Published year: 2024

Published pages: 4525-4540

DOI identifier: 10.1021/acs.jmedchem.3c01820

ISSN: 0022-2623