A Novel Family of Acid-Cleavable Linker Based on Cyclic Acetal Motifs for the Production of Antibody-Drug Conjugates with High Potency and Selectivity

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Authors: Tony Rady; Lorenzo Turelli; Marc Nothisen; Elisabetta Tobaldi; Stéphane Erb; Fabien Thoreau; Oscar Hernandez-Alba; Sarah Cianferani; François Daubeuf; Alain Wagner; Guilhem Chaubet

Journal title: Bioconjugate Chemistry

Journal number: 33

Journal publisher: American Chemical Society

Published year: 2022

Published pages: 1860-1866

DOI identifier: 10.1021/acs.bioconjchem.2c00314

ISSN: 1043-1802