Periodic Reporting for period 1 - STARPAC (STING immune activation and regulation by phosphatidylinositol 4-phosphate-associated components)

In healthy cells, DNA is confined to certain intracellular spaces, including the nucleus. Upon cellular damage, for example from a virus infection, bacterial infection, or tumor formation, DNA is mislocalized to the cytosol. This mislocalized DNA is a danger signal that is...