Periodic Reporting for period 1 - ReverseTheAdvantage (Reversing the advantage of cancers with Hypoxia and Homologous Recombination Defect (HRD) by using a pan-cancer, composite, lesions-specific biomarker)

Deficiencies in certain DNA repair pathways ensure that anti-cancer treatments become more effective. This is exemplified by our previous research showing that tumors with a deficiency in homologous recombination (HR) DNA repair react much better to hypoxia activated prodrug...