A protocol for the assessment of genomic instability in hepatic and lung 3D cell models

A detail protocol for the assessment of genomic instability in hepatic and lung 3D cell models will be prepared as a guideline for testing genotoxic activity of chemicals and nanoparticles. The protocol will contain all the necessary steps and information for the successful performance of the cytokinesis block micronucleus (CBMN) assay on hepatic and lung 3D cell models.