Stromal cells engineered to express T cell factors induce robust CLL cell proliferation in vitro and in PDX co-transplantations allowing the identification of RAF inhibitors as anti-proliferative drug

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Authors: HOFERKOVÁ, Eva, Václav ŠEDA, Soňa CESNÁRIKOVÁ, Jan VERNER, Tomáš LOJA, Květoslava MATULOVÁ, Hana SKUHROVÁ FRANCOVÁ, Eva ONDROUŠKOVÁ, Daniel FILIP, Nicolas BLAVET, Miroslav BOUDNÝ, Gabriela MLADONICKÁ PAVLASOVÁ, Josef VEČEŘA, Laura ONDRIŠOVÁ, Petra PAVELKOVÁ, Kryštof HLAVÁČ, Lenka KOŠŤÁLOVÁ, Androniki MICHAELOU, Šárka POSPÍŠILOVÁ, Jana DORAZILOVÁ, Václav CHOCHOLA

Journal title: Leukemia

Journal number: 14 June 2024

Journal publisher: Nature Publishing Group

Published year: 2024

DOI identifier: 10.1038/s41375-024-02284-w

ISSN: 0887-6924