Periodic Reporting for period 1 - BasicFit (Targeting bicarbonate transport as a “first-in-class” therapeutic strategy to promote CD8+ T cell fitness and enhance cancer immunotherapy)

Although immunotherapies have revolutionized cancer treatment, many patients fail to benefit from them. In this scenario, the complex metabolic crosstalk between the different cells within the tumor microenvironment (TME) is pivotal in regulating immunosuppression and overall...