Periodic Reporting for period 1 - APTADEGRAD (A novel, first-in-its-kind, aptamer-based LYTACs to address the unmet clinical need of diabetic wounds.)

The aim of APTADEGRAD project is to obtain an in vivo proof of concept for a novel, first-in-class therapy using Lysosome Targeting Chimeras (LYTACs) to heal diabetic foot ulcers (DFUs). Diabetic foot ulcers (DFUs), a major complication of diabetes, occur in ~25% of patients...