Identification of 5-(Aryl/Heteroaryl)amino-4-quinolones as Potent Membrane-Disrupting Agents to Combat Antibiotic-Resistant Gram-Positive Bacteria

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Authors: John R. Schultz; Stephen K. Costa; Gorakhnath R. Jachak; Pooja Hegde; Matthew Zimmerman; Yan Pan; Michaele Josten; Chinedu Ejeh; Travis Hammerstad; Hans Georg Sahl; Pedro M. Pereira; Mariana G. Pinho; Véronique Dartois; Ambrose Cheung; Courtney C. Aldrich

Journal title: J Med Chem

Journal number: 2

Journal publisher: American Chemical Society

Published year: 2022

DOI identifier: 10.1021/acs.jmedchem.2c01151

ISSN: 0022-2623