Periodic Reporting for period 1 - Cohesin-Tx (Cohesin Therapeutics. Precision medicine for treating STAG2 mutated cancers)

Summary
The cohesin gene STAG2 has emerged as a significant tumour suppressor, frequently mutated in bladder cancer, Ewing sarcoma, and acute myeloid leukaemia (AML). Currently, these cancers are treated by cytotoxic therapies and surgery. These treatment plans are limited by unwanted...