Periodic Reporting for period 1 - SorCS (Structural and biophysical characterisation of insulin receptor and glutamate receptors AMPAR and NMDAR in complex with SorCS coreceptors 1 and 2)

Sortilin related CNS expressed receptor (SorCS) 1, 2 and 3, members of the Vacuolar Protein Sorting 10 protein (VPS10p) family, are neural sorting receptors that play a central role in control of neuronal viability and function by sorting crucial proteins. Reduced trafficking...