Periodic Reporting for period 1 - ADC2GBM (Development of brain-permeable masked nanobody-drug conjugates to eliminate glioma stem cells)

Summary
Glioblastoma multiforme (GBM) is the most prevalent and aggressive brain tumour. GBM is the second cause of death from neurological diseases and accounts for 4% of cancer associated deaths. Despite surgical tumour resection followed by chemotherapy and radiotherapy, life...