Design, synthesis, and biological evaluation of first-in-class indomethacin-based PROTACs degrading SARS-CoV-2 main protease and with broad-spectrum antiviral activity

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Authors: Jenny Desantis, Alessandro Bazzacco, Michela Eleuteri, Sara Tuci, Elisa Bianconi, Antonio Macchiarulo, Beatrice Mercorelli, Arianna Loregian, Laura Goracci 

Journal title: European Journal of Medicinal Chemistry

Journal publisher: American Chemical Society

Published year: 2024

DOI identifier: 10.1016/j.ejmech.2024.116202

ISSN: 1768-3254