High-throughput chemogenetic drug screening reveals PKC-RhoA/PKN as a targetable signaling vulnerability in GNAQ-driven uveal melanoma

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Authors: Nadia Arang , Simone Lubrano , Michele Ceribelli , Damiano C Rigiracciolo , Robert Saddawi-Konefka , Farhoud Faraji , Sydney I Ramirez , Daehwan Kim , Frances A Tosto , Erica Stevenson , Yuan Zhou , Zhiyong Wang , Julius Bogomolovas , Alfredo A Molinolo , Danielle L Swaney , Nevan J Krogan , Jing Yang , Silvia Coma , Jonathan A Pachter , Andrew E Aplin , Dario R Alessi , Craig J Thomas , J Silvio

Journal title: Cell Reports Medicine

Journal publisher: New York: Cell Pres Elsevier Inc.

Published year: 2023

DOI identifier: 10.1016/j.xcrm.2023.101244

ISSN: 2666-3791