Genome editing with the HDR-enhancing DNA-PKcs inhibitor AZD7648 causes large-scale genomic alterations

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Authors: Grégoire Cullot, Eric J. Aird, Moritz F. Schlapansky, Charles D. Yeh, Lilly van de Venn, Iryna Vykhlyantseva, Susanne Kreutzer, Dominic Mailänder, Bohdan Lewków, Julia Klermund, Christian Montellese, Martina Biserni, Florian Aeschimann, Cédric Vonarburg, Helmuth Gehart, Toni Cathomen, Jacob E. Corn

Journal title: Nature Biotechnology

Journal publisher: Springer Science and Business Media LLC

Published year: 2024

DOI identifier: 10.1038/S41587-024-02488-6

ISSN: 1087-0156