eFUS chip: Biological/histological evidence of efficacy

The report will include the first in vivo results using the eFUS chip manufactured by the consortium. The eFUS chip will be implanted and the animals will recover, and will be stimulated over 5 days according to pre-determined parameters. Histological methods will describe the biological effects of the eFUS (e.g. c-fos, TUNNEL, inflammation markers, etc). Molecular methods will describe regional changes in gene expression in key areas (mPFC, NAc).