Periodic Reporting for period 1 - StructureSND (Structural basis for membrane protein biogenesis at the Endoplasmic reticulum by the SND pathway)

One-third of eukaryotic genes encode for integral membrane proteins (IMPs) with the majority being assembled at the endoplasmic reticulum (ER) after being translated by the ribosome. The SRP-independent (SND) targeting pathway was recently identified as a new route for ER...