Periodic Reporting for period 4 - MegaALS (Unravelling the Interplay between Metabolism, Gut Microbiome and Adaptive Immunity in Amyotrophic Lateral Sclerosis)

1. What is the problem/issue being addressed?Amyotrophic lateral sclerosis (ALS) is now recognized as a systemic disease affecting both the central nervous system (CNS) and whole-body physiology. Understanding its etiology requires investigating CNS interactions with other...