Anti–PD-1 cancer immunotherapy induces central nervous system immune-related adverse events by microglia activation

Summary

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Authors: Janaki Manoja Vinnakota, Rachael C. Adams, Dimitrios Athanassopoulos, Dominik Schmidt, Francesca Biavasco, Alexander Zähringer, Daniel Erny, Marius Schwabenland, Marlene Langenbach, Valentin Wenger, Henrike Salié, James Cook, Omar Mossad, Geoffroy Andrieux, Rick Dersch, Sebastian Rauer, Sandra Duquesne, Gianni Monaco, Phillipp Wolf, Thomas Blank, Philipp Häne, Melanie Greter, Burkhard Becher, Philipp Henneke, Dietmar Pfeifer, Bruce R. Blazar, Justus Duyster, Melanie Boerries, Natalie Köhler, Chintan M. Chhatbar, Bertram Bengsch, Marco Prinz, Robert Zeiser

Journal title: Science Translational Medicine

Journal number: 16

Journal publisher: American Association for the Advancement of Science (AAAS)

Published year: 2024

DOI identifier: 10.1126/SCITRANSLMED.ADJ9672

ISSN: 1946-6234