Periodic Reporting for period 1 - SpinSAC (hSpindly, a new regulatory protein of the SAC mechanism and its implication in tumour therapy)

During mitosis a surveillance system, known as the spindle assembly checkpoint (SAC), is crucial to make sure that the cell does not separate its sister chromatids until all the chromosomes are correctly attached to spindle microtubules and bi-oriented. Nowadays, one of the...