Periodic Reporting for period 5 - FAIR-PARK-II (Conservative iron chelation as a disease-modifying strategy in Parkinson’s disease: a multicentric, parallel-group, placebo-controlled, randomized clinical trial of deferiprone)

In Parkinson’s disease (PD), excess iron is detected in the substantia nigra pars compacta, where dopaminergic neurons are exposed to high levels of oxidative stress. Pilot clinical studies demonstrated that iron chelation therapy with the deferiprone (DFP): induces...