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Project: SILICOFCM

Updated at: 29-04-2024

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Project acronym SILICOFCM

Variational Gaussian Mixture Models with robust Dirichlet concentration priors for virtual population generation in hype...

Project: SILICOFCM

Updated at: 29-04-2024

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Project acronym SILICOFCM

Identification of sequence changes in myosin II that adjust muscle contraction velocity

Project: SILICOFCM

Updated at: 29-04-2024

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Project acronym SILICOFCM

Inhibitory potency of Valsartan/Sacubitril drug combination: molecular docking simulations

Project: SILICOFCM

Updated at: 29-04-2024

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Project acronym SILICOFCM

Mavacamten has a differential impact on force generation in myofibrils from rabbit psoas and human cardiac muscle

Project: SILICOFCM

Updated at: 29-04-2024

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Project acronym SILICOFCM

Myosin motor domains carrying mutations implicated in early or late onset hypertrophic cardiomyopathy have similar prope...

Project: SILICOFCM

Updated at: 29-04-2024

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Project acronym SILICOFCM

Imaging acquisition data

Project: SILICOFCM

Updated at: 29-04-2024

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Project acronym SILICOFCM

Generation of virtual patients for in silico cardiomyopathies drug development

Project: SILICOFCM

Updated at: 29-04-2024

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Project acronym SILICOFCM

Cryo-EM and Molecular Docking Shows Myosin Loop 4 Contacts Actin and Tropomyosin on Thin Filaments

Project: SILICOFCM

Updated at: 29-04-2024

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Project acronym SILICOFCM

Contemporary Insights Into the Genetics of Hypertrophic Cardiomyopathy: Toward a New Era in Clinical Testing?

Project: SILICOFCM

Updated at: 29-04-2024

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Project acronym SILICOFCM

Semi-Automatic Left Ventricle Model Generation

Project: SILICOFCM

Updated at: 29-04-2024

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Project acronym SILICOFCM

Project Website

Project: SILICOFCM

Updated at: 29-04-2024

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Project acronym SILICOFCM

Insights into heart failure hospitalizations, management, and services during and beyond COVID‐19

Project: SILICOFCM

Updated at: 29-04-2024

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Project acronym SILICOFCM

Estimation of Forces on Actin Filaments in Living Muscle from X-ray Diffraction Patterns and Mechanical Data

Project: SILICOFCM

Updated at: 29-04-2024

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Project acronym SILICOFCM

Optical Investigation of Action Potential and Calcium Handling Maturation of hiPSC-Cardiomyocytes on Biomimetic Substrat...

Project: SILICOFCM

Updated at: 29-04-2024

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Project acronym SILICOFCM

Road map on Business Model v2

Project: SILICOFCM

Updated at: 29-04-2024

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Project acronym SILICOFCM

Computational Modeling of Sarcomere Protein Mutations and Drug Effects on Cardiac Muscle Behavior

Project: SILICOFCM

Updated at: 29-04-2024

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Project acronym SILICOFCM

Generation of virtual patient data for in-silico cardiomyopathies drug development using tree ensembles: a comparative s...

Project: SILICOFCM

Updated at: 29-04-2024

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Project acronym SILICOFCM

3D reconstruction and computational modeling of solid-fluid interaction in realistic heart model

Project: SILICOFCM

Updated at: 29-04-2024

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Project acronym SILICOFCM

Exploring the super-relaxed state of myosin in myofibrils from fast-twitch, slow-twitch, and cardiac muscle

Project: SILICOFCM

Updated at: 29-04-2024

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Project acronym SILICOFCM

Multi-scale striated muscle contraction model linking sarcomere length-dependent cross-bridge kinetics to macroscopic de...

Project: SILICOFCM

Updated at: 29-04-2024

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Project acronym SILICOFCM

Tuning Cooperativity of Calcium Activation in Cardiac Muscle

Project: SILICOFCM

Updated at: 29-04-2024

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Project acronym SILICOFCM

Heart Mechanical Model Based on Holzapfel Experiments

Project: SILICOFCM

Updated at: 29-04-2024

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Project acronym SILICOFCM

Modulation of post-powerstroke dynamics in myosin II by 2′-deoxy-ADP

Project: SILICOFCM

Updated at: 29-04-2024

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Project acronym SILICOFCM

FLUID-ELECTRO-MECHANICAL PARAMETRIC MODEL OF THE LEFT VENTRICLE

Project: SILICOFCM

Updated at: 29-04-2024

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Project acronym SILICOFCM

Requirements Analysis

Project: SILICOFCM

Updated at: 29-04-2024

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Project acronym SILICOFCM

Pediatric and adult-onset HCM mutations in the myosin motor domain have similar properties

Project: SILICOFCM

Updated at: 29-04-2024

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Project acronym SILICOFCM

The homozygous K280N troponin T mutation alters cross-bridge kinetics and energetics in human HCM

Project: SILICOFCM

Updated at: 29-04-2024

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Project acronym SILICOFCM

Advanced Morpho-Functional Analysis on Ventricular and Atrial Tissue Reveals Cross-Bridge Kinetics Alterations and Sarco...

Project: SILICOFCM

Updated at: 29-04-2024

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Project acronym SILICOFCM

Nebulin and titin modulate cross-bridge cycling and length-dependent calcium sensitivity

Project: SILICOFCM

Updated at: 29-04-2024

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Project acronym SILICOFCM

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Project videos

Variational Gaussian Mixture Models with robust Dirichlet concentration priors for virtual population generation in hype...

Identification of sequence changes in myosin II that adjust muscle contraction velocity

Inhibitory potency of Valsartan/Sacubitril drug combination: molecular docking simulations

Mavacamten has a differential impact on force generation in myofibrils from rabbit psoas and human cardiac muscle

Myosin motor domains carrying mutations implicated in early or late onset hypertrophic cardiomyopathy have similar prope...

Imaging acquisition data

Generation of virtual patients for in silico cardiomyopathies drug development

Cryo-EM and Molecular Docking Shows Myosin Loop 4 Contacts Actin and Tropomyosin on Thin Filaments

Contemporary Insights Into the Genetics of Hypertrophic Cardiomyopathy: Toward a New Era in Clinical Testing?

Semi-Automatic Left Ventricle Model Generation

Project Website

Insights into heart failure hospitalizations, management, and services during and beyond COVID‐19

Estimation of Forces on Actin Filaments in Living Muscle from X-ray Diffraction Patterns and Mechanical Data

Optical Investigation of Action Potential and Calcium Handling Maturation of hiPSC-Cardiomyocytes on Biomimetic Substrat...

Road map on Business Model v2

Computational Modeling of Sarcomere Protein Mutations and Drug Effects on Cardiac Muscle Behavior

Generation of virtual patient data for in-silico cardiomyopathies drug development using tree ensembles: a comparative s...

3D reconstruction and computational modeling of solid-fluid interaction in realistic heart model

Exploring the super-relaxed state of myosin in myofibrils from fast-twitch, slow-twitch, and cardiac muscle

Multi-scale striated muscle contraction model linking sarcomere length-dependent cross-bridge kinetics to macroscopic de...

Tuning Cooperativity of Calcium Activation in Cardiac Muscle

Heart Mechanical Model Based on Holzapfel Experiments

Modulation of post-powerstroke dynamics in myosin II by 2′-deoxy-ADP

FLUID-ELECTRO-MECHANICAL PARAMETRIC MODEL OF THE LEFT VENTRICLE

Requirements Analysis

Pediatric and adult-onset HCM mutations in the myosin motor domain have similar properties

The homozygous K280N troponin T mutation alters cross-bridge kinetics and energetics in human HCM

Advanced Morpho-Functional Analysis on Ventricular and Atrial Tissue Reveals Cross-Bridge Kinetics Alterations and Sarco...

Nebulin and titin modulate cross-bridge cycling and length-dependent calcium sensitivity