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Variational Gaussian Mixture Models with robust Dirichlet concentration priors for virtual population generation in hype...

Project: SILICOFCM

Updated at: 29-04-2024

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Project acronym SILICOFCM

Identification of sequence changes in myosin II that adjust muscle contraction velocity

Project: SILICOFCM

Updated at: 29-04-2024

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Project acronym SILICOFCM

Myosin motor domains carrying mutations implicated in early or late onset hypertrophic cardiomyopathy have similar prope...

Project: SILICOFCM

Updated at: 29-04-2024

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Project acronym SILICOFCM

Semi-Automatic Left Ventricle Model Generation

Project: SILICOFCM

Updated at: 29-04-2024

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Project acronym SILICOFCM

Cryo-EM and Molecular Docking Shows Myosin Loop 4 Contacts Actin and Tropomyosin on Thin Filaments

Project: SILICOFCM

Updated at: 29-04-2024

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Project acronym SILICOFCM

Generation of virtual patients for in silico cardiomyopathies drug development

Project: SILICOFCM

Updated at: 29-04-2024

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Mavacamten has a differential impact on force generation in myofibrils from rabbit psoas and human cardiac muscle

Project: SILICOFCM

Updated at: 29-04-2024

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Project acronym SILICOFCM

Contemporary Insights Into the Genetics of Hypertrophic Cardiomyopathy: Toward a New Era in Clinical Testing?

Project: SILICOFCM

Updated at: 29-04-2024

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Project acronym SILICOFCM

Inhibitory potency of Valsartan/Sacubitril drug combination: molecular docking simulations

Project: SILICOFCM

Updated at: 29-04-2024

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Project Website

Project: SILICOFCM

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Project acronym SILICOFCM

Imaging acquisition data

Project: SILICOFCM

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Project: SILICOFCM

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FLUID-ELECTRO-MECHANICAL PARAMETRIC MODEL OF THE LEFT VENTRICLE

Project: SILICOFCM

Updated at: 29-04-2024

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Project acronym SILICOFCM

3D reconstruction and computational modeling of solid-fluid interaction in realistic heart model

Project: SILICOFCM

Updated at: 29-04-2024

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Requirements Analysis

Project: SILICOFCM

Updated at: 29-04-2024

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Computational Modeling of Sarcomere Protein Mutations and Drug Effects on Cardiac Muscle Behavior

Project: SILICOFCM

Updated at: 29-04-2024

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Project acronym SILICOFCM

Insights into heart failure hospitalizations, management, and services during and beyond COVID‐19

Project: SILICOFCM

Updated at: 29-04-2024

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Multi-scale striated muscle contraction model linking sarcomere length-dependent cross-bridge kinetics to macroscopic de...

Project: SILICOFCM

Updated at: 29-04-2024

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Optical Investigation of Action Potential and Calcium Handling Maturation of hiPSC-Cardiomyocytes on Biomimetic Substrat...

Project: SILICOFCM

Updated at: 29-04-2024

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Road map on Business Model v2

Project: SILICOFCM

Updated at: 29-04-2024

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Estimation of Forces on Actin Filaments in Living Muscle from X-ray Diffraction Patterns and Mechanical Data

Project: SILICOFCM

Updated at: 29-04-2024

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Tuning Cooperativity of Calcium Activation in Cardiac Muscle

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Updated at: 29-04-2024

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Heart Mechanical Model Based on Holzapfel Experiments

Project: SILICOFCM

Updated at: 29-04-2024

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Project acronym SILICOFCM

Generation of virtual patient data for in-silico cardiomyopathies drug development using tree ensembles: a comparative s...

Project: SILICOFCM

Updated at: 29-04-2024

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Project acronym SILICOFCM

Modulation of post-powerstroke dynamics in myosin II by 2′-deoxy-ADP

Project: SILICOFCM

Updated at: 29-04-2024

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Project acronym SILICOFCM

Exploring the super-relaxed state of myosin in myofibrils from fast-twitch, slow-twitch, and cardiac muscle

Project: SILICOFCM

Updated at: 29-04-2024

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Project acronym SILICOFCM

The homozygous K280N troponin T mutation alters cross-bridge kinetics and energetics in human HCM

Project: SILICOFCM

Updated at: 29-04-2024

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Nebulin and titin modulate cross-bridge cycling and length-dependent calcium sensitivity

Project: SILICOFCM

Updated at: 29-04-2024

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Electrophysiological and Contractile Effects of Disopyramide in Patients With Obstructive Hypertrophic Cardiomyopathy

Project: SILICOFCM

Updated at: 29-04-2024

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Project acronym SILICOFCM

Physiological experiments

Project: SILICOFCM

Updated at: 29-04-2024

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Project acronym SILICOFCM

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Variational Gaussian Mixture Models with robust Dirichlet concentration priors for virtual population generation in hype...

Identification of sequence changes in myosin II that adjust muscle contraction velocity

Myosin motor domains carrying mutations implicated in early or late onset hypertrophic cardiomyopathy have similar prope...

Semi-Automatic Left Ventricle Model Generation

Cryo-EM and Molecular Docking Shows Myosin Loop 4 Contacts Actin and Tropomyosin on Thin Filaments

Generation of virtual patients for in silico cardiomyopathies drug development

Mavacamten has a differential impact on force generation in myofibrils from rabbit psoas and human cardiac muscle

Contemporary Insights Into the Genetics of Hypertrophic Cardiomyopathy: Toward a New Era in Clinical Testing?

Inhibitory potency of Valsartan/Sacubitril drug combination: molecular docking simulations

Project Website

Imaging acquisition data

Project videos

FLUID-ELECTRO-MECHANICAL PARAMETRIC MODEL OF THE LEFT VENTRICLE

3D reconstruction and computational modeling of solid-fluid interaction in realistic heart model

Requirements Analysis

Computational Modeling of Sarcomere Protein Mutations and Drug Effects on Cardiac Muscle Behavior

Insights into heart failure hospitalizations, management, and services during and beyond COVID‐19

Multi-scale striated muscle contraction model linking sarcomere length-dependent cross-bridge kinetics to macroscopic de...

Optical Investigation of Action Potential and Calcium Handling Maturation of hiPSC-Cardiomyocytes on Biomimetic Substrat...

Road map on Business Model v2

Estimation of Forces on Actin Filaments in Living Muscle from X-ray Diffraction Patterns and Mechanical Data

Tuning Cooperativity of Calcium Activation in Cardiac Muscle

Heart Mechanical Model Based on Holzapfel Experiments

Generation of virtual patient data for in-silico cardiomyopathies drug development using tree ensembles: a comparative s...

Modulation of post-powerstroke dynamics in myosin II by 2′-deoxy-ADP

Exploring the super-relaxed state of myosin in myofibrils from fast-twitch, slow-twitch, and cardiac muscle

The homozygous K280N troponin T mutation alters cross-bridge kinetics and energetics in human HCM

Nebulin and titin modulate cross-bridge cycling and length-dependent calcium sensitivity

Electrophysiological and Contractile Effects of Disopyramide in Patients With Obstructive Hypertrophic Cardiomyopathy

Physiological experiments