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Induced pluripotent stem cells and hematological malignancies: A powerful tool for disease modeling and drug development

Project: SilkFUSION

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New Challenges for Biobanks: Accreditation to the New ISO 20387:2018 Standard Specific for Biobanks

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Project acronym SilkFUSION

Novel variants in GALE caused syndromic macrothrombocytopenia disrupting thrombopoiesis and glycosylation

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Project acronym SilkFUSION

Supercharged platelets as a novel therapy for reducing blood loss post-cardiac surgery

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Scientific papers_48

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Structurally graduated collagen scaffolds applied to the ex vivo generation of platelets from human pluripotent stem cel...

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Pathogenetic and clinical study of a patient with thrombocytopenia due to the p.E527K gain-of-function variant of SRC

Project: SilkFUSION

Updated at: 27-04-2024

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Project acronym SilkFUSION

Multi-channel silk sponge mimicking bone marrow vascular niche for platelet production

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Disrupted filamin A/αIIbβ3 interaction induces macrothrombocytopenia by increasing RhoA activity

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Miniaturized 3D bone marrow tissue model to assess response to Thrombopoietin-receptor agonists in patients

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Mechanisms of platelet release: in vivo studies and in vitro modeling

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In vitro-derived platelets: the challenges we will have to face to assess quality and safety

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Periodic Reporting for period 3 - SilkFUSION (Genetically engineered human pluripotent stem cells, functionalized silk-f...

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Workshops_24

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Scientific papers_12

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Thyroid hormones and analogues promote the acute release of platelets from megakaryocytes: from blood donor biology to t...

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Project acronym SilkFUSION

Role of Rho-GTPases in megakaryopoiesis

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Bioengineering a 3D silk platform for large-scale platelet production

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SYSTEMS AND METHODS FOR ASSESSING PATIENT-SPECIFIC RESPONSE TO THROMBOPOIETIN-RECEPTOR AGONISTS

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SILK FIBROIN AND RELATED USE FOR 3D BIOPRINTING

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Novel variants in GALE cause syndromic macrothrombocytopenia by disrupting glycosylation and thrombopoiesis

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Project acronym SilkFUSION

ANKRD26 is a new regulator of type I cytokine receptor signaling in normal and pathological hematopoiesis

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Latest culture techniques: cracking the secrets of bone marrow to mass-produce erythrocytes and platelets <i>ex vivo

Project: SilkFUSION

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Illustrated State-of-the-Art Capsules of the ISTH 2022 Congress - Megakaryocytes and different thrombopoietic environmen...

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Targeted stakeholders identified and informed about the project_12

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Targeted stakeholders identified and informed about the project_24

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Public Project website

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Workshops_12

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Scientific papers_36

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Induced pluripotent stem cells and hematological malignancies: A powerful tool for disease modeling and drug development

New Challenges for Biobanks: Accreditation to the New ISO 20387:2018 Standard Specific for Biobanks

Novel variants in GALE caused syndromic macrothrombocytopenia disrupting thrombopoiesis and glycosylation

Supercharged platelets as a novel therapy for reducing blood loss post-cardiac surgery

Project video targeting a wide public audience

Scientific papers_48

Structurally graduated collagen scaffolds applied to the ex vivo generation of platelets from human pluripotent stem cel...

Pathogenetic and clinical study of a patient with thrombocytopenia due to the p.E527K gain-of-function variant of SRC

Multi-channel silk sponge mimicking bone marrow vascular niche for platelet production

Disrupted filamin A/αIIbβ3 interaction induces macrothrombocytopenia by increasing RhoA activity

Miniaturized 3D bone marrow tissue model to assess response to Thrombopoietin-receptor agonists in patients

Mechanisms of platelet release: in vivo studies and in vitro modeling

In vitro-derived platelets: the challenges we will have to face to assess quality and safety

Periodic Reporting for period 3 - SilkFUSION (Genetically engineered human pluripotent stem cells, functionalized silk-f...

Workshops_24

Scientific papers_12

Thyroid hormones and analogues promote the acute release of platelets from megakaryocytes: from blood donor biology to t...

Role of Rho-GTPases in megakaryopoiesis

Bioengineering a 3D silk platform for large-scale platelet production

SYSTEMS AND METHODS FOR ASSESSING PATIENT-SPECIFIC RESPONSE TO THROMBOPOIETIN-RECEPTOR AGONISTS

SILK FIBROIN AND RELATED USE FOR 3D BIOPRINTING

Novel variants in GALE cause syndromic macrothrombocytopenia by disrupting glycosylation and thrombopoiesis

ANKRD26 is a new regulator of type I cytokine receptor signaling in normal and pathological hematopoiesis

Latest culture techniques: cracking the secrets of bone marrow to mass-produce erythrocytes and platelets <i>ex vivo

Illustrated State-of-the-Art Capsules of the ISTH 2022 Congress - Megakaryocytes and different thrombopoietic environmen...

Targeted stakeholders identified and informed about the project_12

Targeted stakeholders identified and informed about the project_24

Public Project website

Workshops_12

Scientific papers_36