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Elevated Prolactin during Pregnancy Drives a Phenotypic Switch in Mouse Hypothalamic Dopaminergic Neurons

Project: OptoBETA

Updated at: 27-04-2024

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Project acronym OptoBETA

Informing β-cell regeneration strategies using studies of heterogeneity

Project: OptoBETA

Updated at: 27-04-2024

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Project acronym OptoBETA

Dimerization of the Sodium/Iodide Symporter

Project: OptoBETA

Updated at: 27-04-2024

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Project acronym OptoBETA

A unique androgen excess signature in idiopathic intracranial hypertension is linked to cerebrospinal fluid dynamics

Project: OptoBETA

Updated at: 27-04-2024

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Project acronym OptoBETA

The type 2 diabetes gene product STARD10 is a phosphoinositide binding protein that controls insulin secretory granule b...

Project: OptoBETA

Updated at: 27-04-2024

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Project acronym OptoBETA

Maternal hypothyroidism in mice influences glucose metabolism in adult offspring

Project: OptoBETA

Updated at: 27-04-2024

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Project acronym OptoBETA

AMPK activation induces mitophagy and promotes mitochondrial fission while activating TBK1 in a PINK1‐Parkin independe...

Project: OptoBETA

Updated at: 27-04-2024

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Project acronym OptoBETA

The Influence of Peptide Context on Signaling and Trafficking of Glucagon-like Peptide-1 Receptor Biased Agonists

Project: OptoBETA

Updated at: 27-04-2024

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Project acronym OptoBETA

Super-resolution microscopy compatible fluorescent probes reveal endogenous glucagon-like peptide-1 receptor distributio...

Project: OptoBETA

Updated at: 27-04-2024

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Project acronym OptoBETA

PDX1LOW MAFALOW β-cells contribute to islet function and insulin release

Project: OptoBETA

Updated at: 27-04-2024

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Project acronym OptoBETA

Signalling, trafficking and glucoregulatory properties of glucagon‐like peptide‐1 receptor agonists exendin‐4 and ...

Project: OptoBETA

Updated at: 27-04-2024

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Project acronym OptoBETA

Interrogating surface versus intracellular transmembrane receptor populations using cell-impermeable SNAP-tag substrates

Project: OptoBETA

Updated at: 27-04-2024

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Project acronym OptoBETA

A Variation on the Theme: SGLT2 Inhibition and Glucagon Secretion in Human Islets

Project: OptoBETA

Updated at: 27-04-2024

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Project acronym OptoBETA

GLP1R Attenuates Sympathetic Response to High Glucose via Carotid Body Inhibition

Project: OptoBETA

Updated at: 27-04-2024

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Project acronym OptoBETA

Optical control of GPR40 signalling in pancreatic β-cells

Project: OptoBETA

Updated at: 27-04-2024

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Project acronym OptoBETA

The transcription factor Pax6 is required for pancreatic β cell identity, glucose-regulated ATP synthesis, and Ca 2+ dy...

Project: OptoBETA

Updated at: 27-04-2024

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Project acronym OptoBETA

New Understanding of β-Cell Heterogeneity and In Situ Islet Function

Project: OptoBETA

Updated at: 27-04-2024

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Project acronym OptoBETA

Structure-functional changes in eNAMPT at high concentrations mediate mouse and human beta cell dysfunction in type 2 di...

Project: OptoBETA

Updated at: 27-04-2024

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Project acronym OptoBETA

Oncogenic IDH1 Mutations Promote Enhanced Proline Synthesis through PYCR1 to Support the Maintenance of Mitochondrial Re...

Project: OptoBETA

Updated at: 27-04-2024

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Project acronym OptoBETA

Conditional and Reversible Activation of Class A and B G Protein-Coupled Receptors Using Tethered Pharmacology

Project: OptoBETA

Updated at: 27-04-2024

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Project acronym OptoBETA

Optical tools for understanding the complexity of β-cell signalling and insulin release

Project: OptoBETA

Updated at: 27-04-2024

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Project acronym OptoBETA

Androgen excess in pancreatic β cells and neurons predisposes female mice to type 2 diabetes

Project: OptoBETA

Updated at: 27-04-2024

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Project acronym OptoBETA

The Impact of Pancreatic Beta Cell Heterogeneity on Type 1 Diabetes Pathogenesis

Project: OptoBETA

Updated at: 27-04-2024

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Project acronym OptoBETA

The role of beta cell heterogeneity in islet function and insulin release

Project: OptoBETA

Updated at: 27-04-2024

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Project acronym OptoBETA

Remote control of glucose homeostasis in vivo using photopharmacology

Project: OptoBETA

Updated at: 27-04-2024

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Project acronym OptoBETA

Optical control of a receptor-linked guanylyl cyclase using a photoswitchable peptidic hormone

Project: OptoBETA

Updated at: 27-04-2024

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Project acronym OptoBETA

Age-related islet inflammation marks the proliferative decline of pancreatic beta-cells in zebrafish

Project: OptoBETA

Updated at: 27-04-2024

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Project acronym OptoBETA

RAMP2 Influences Glucagon Receptor Pharmacology via Trafficking and Signaling

Project: OptoBETA

Updated at: 27-04-2024

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Project acronym OptoBETA

Potent Prearranged Positive Allosteric Modulators of the Glucagon-like Peptide-1 Receptor

Project: OptoBETA

Updated at: 27-04-2024

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Project acronym OptoBETA

Glucagon-like peptide-1 receptor regulates thromboxane-induced human platelet activation

Project: OptoBETA

Updated at: 27-04-2024

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Project acronym OptoBETA

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Elevated Prolactin during Pregnancy Drives a Phenotypic Switch in Mouse Hypothalamic Dopaminergic Neurons

Informing β-cell regeneration strategies using studies of heterogeneity

Dimerization of the Sodium/Iodide Symporter

A unique androgen excess signature in idiopathic intracranial hypertension is linked to cerebrospinal fluid dynamics

The type 2 diabetes gene product STARD10 is a phosphoinositide binding protein that controls insulin secretory granule b...

Maternal hypothyroidism in mice influences glucose metabolism in adult offspring

AMPK activation induces mitophagy and promotes mitochondrial fission while activating TBK1 in a PINK1‐Parkin independe...

The Influence of Peptide Context on Signaling and Trafficking of Glucagon-like Peptide-1 Receptor Biased Agonists

Super-resolution microscopy compatible fluorescent probes reveal endogenous glucagon-like peptide-1 receptor distributio...

PDX1LOW MAFALOW β-cells contribute to islet function and insulin release

Signalling, trafficking and glucoregulatory properties of glucagon‐like peptide‐1 receptor agonists exendin‐4 and ...

Interrogating surface versus intracellular transmembrane receptor populations using cell-impermeable SNAP-tag substrates

A Variation on the Theme: SGLT2 Inhibition and Glucagon Secretion in Human Islets

GLP1R Attenuates Sympathetic Response to High Glucose via Carotid Body Inhibition

Optical control of GPR40 signalling in pancreatic β-cells

The transcription factor Pax6 is required for pancreatic β cell identity, glucose-regulated ATP synthesis, and Ca 2+ dy...

New Understanding of β-Cell Heterogeneity and In Situ Islet Function

Structure-functional changes in eNAMPT at high concentrations mediate mouse and human beta cell dysfunction in type 2 di...

Oncogenic IDH1 Mutations Promote Enhanced Proline Synthesis through PYCR1 to Support the Maintenance of Mitochondrial Re...

Conditional and Reversible Activation of Class A and B G Protein-Coupled Receptors Using Tethered Pharmacology

Optical tools for understanding the complexity of β-cell signalling and insulin release

Androgen excess in pancreatic β cells and neurons predisposes female mice to type 2 diabetes

The Impact of Pancreatic Beta Cell Heterogeneity on Type 1 Diabetes Pathogenesis

The role of beta cell heterogeneity in islet function and insulin release

Remote control of glucose homeostasis in vivo using photopharmacology

Optical control of a receptor-linked guanylyl cyclase using a photoswitchable peptidic hormone

Age-related islet inflammation marks the proliferative decline of pancreatic beta-cells in zebrafish

RAMP2 Influences Glucagon Receptor Pharmacology via Trafficking and Signaling

Potent Prearranged Positive Allosteric Modulators of the Glucagon-like Peptide-1 Receptor

Glucagon-like peptide-1 receptor regulates thromboxane-induced human platelet activation