ERD

Biocatalysis

Project: NetMoDEzyme

Updated at: 27-04-2024

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Project acronym NetMoDEzyme

Synthesis, In Vitro Profiling, and In Vivo Evaluation of Benzohomoadamantane-Based Ureas for Visceral Pain: A New Indica...

Project: NetMoDEzyme

Updated at: 27-04-2024

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Project acronym NetMoDEzyme

Inducing high activity of a thermophilic enzyme at ambient temperatures by directed evolution

Project: NetMoDEzyme

Updated at: 27-04-2024

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Project acronym NetMoDEzyme

Deciphering the Allosterically Driven Conformational Ensemble in Tryptophan Synthase Evolution

Project: NetMoDEzyme

Updated at: 27-04-2024

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Project acronym NetMoDEzyme

Exploring the origins of selectivity in soluble epoxide hydrolase from Bacillus megaterium

Project: NetMoDEzyme

Updated at: 27-04-2024

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Project acronym NetMoDEzyme

Exploring the reversal of enantioselectivity on a zinc-dependent alcohol dehydrogenase

Project: NetMoDEzyme

Updated at: 27-04-2024

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Project acronym NetMoDEzyme

In Silico Identification and Experimental Validation of Distal Activity-Enhancing Mutations in Tryptophan Synthase.

Project: NetMoDEzyme

Updated at: 27-04-2024

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Project acronym NetMoDEzyme

Role of Conformational Dynamics in the Evolution of Retro-Aldolase Activity

Project: NetMoDEzyme

Updated at: 27-04-2024

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Project acronym NetMoDEzyme

Computational tools for the evaluation of laboratory-engineered biocatalysts

Project: NetMoDEzyme

Updated at: 27-04-2024

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Project acronym NetMoDEzyme

The challenge of predicting distal active site mutations in computational enzyme design

Project: NetMoDEzyme

Updated at: 27-04-2024

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Project acronym NetMoDEzyme

Mutational Analysis of Linalool Dehydratase Isomerase Suggests That Alcohol and Alkene Transformations Are Catalyzed Usi...

Project: NetMoDEzyme

Updated at: 27-04-2024

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Project acronym NetMoDEzyme

Pervasive cooperative mutational effects on multiple catalytic enzyme traits emerge via long-range conformational dynami...

Project: NetMoDEzyme

Updated at: 27-04-2024

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Project acronym NetMoDEzyme

Estimating conformational heterogeneity of tryptophan synthase with a template-based Alphafold2 approach

Project: NetMoDEzyme

Updated at: 27-04-2024

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Project acronym NetMoDEzyme

2-Oxaadamant-1-yl Ureas as Soluble Epoxide Hydrolase Inhibitors: In Vivo Evaluation in a Murine Model of Acute Pancreati...

Project: NetMoDEzyme

Updated at: 27-04-2024

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Project acronym NetMoDEzyme

Hidden Conformations in Aspergillus niger Monoamine Oxidase are Key for Catalytic Efficiency

Project: NetMoDEzyme

Updated at: 27-04-2024

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Project acronym NetMoDEzyme

p38γ is essential for cell cycle progression and liver tumorigenesis

Project: NetMoDEzyme

Updated at: 27-04-2024

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Project acronym NetMoDEzyme

SBMOpenMM: A Builder of Structure-Based Models for OpenMM.

Project: NetMoDEzyme

Updated at: 27-04-2024

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Project acronym NetMoDEzyme

Epoxide Hydrolase Conformational Heterogeneity for the Resolution of Bulky Pharmacologically Relevant Epoxide Substrates

Project: NetMoDEzyme

Updated at: 27-04-2024

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Project acronym NetMoDEzyme

Role of conformational dynamics in the evolution of novel enzyme function

Project: NetMoDEzyme

Updated at: 27-04-2024

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Project acronym NetMoDEzyme

Time Evolution of the Millisecond Allosteric Activation of Imidazole Glycerol Phosphate Synthase

Project: NetMoDEzyme

Updated at: 27-04-2024

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Project acronym NetMoDEzyme

Periodic Reporting for period 5 - NetMoDEzyme (Network models for the computational design of proficient enzymes)

Project: NetMoDEzyme

Updated at: 27-04-2024

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Project acronym NetMoDEzyme

Discovery and in Vivo Proof of Concept of a Highly Potent Dual Inhibitor of Soluble Epoxide Hydrolase and Acetylcholines...

Project: NetMoDEzyme

Updated at: 27-04-2024

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Project acronym NetMoDEzyme

In Vivo Selection for Formate Dehydrogenases with High Efficiency and Specificity toward NADP +

Project: NetMoDEzyme

Updated at: 27-04-2024

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Project acronym NetMoDEzyme

From the Design to the In Vivo Evaluation of Benzohomoadamantane-Derived Soluble Epoxide Hydrolase Inhibitors for the Tr...

Project: NetMoDEzyme

Updated at: 27-04-2024

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Project acronym NetMoDEzyme

Insights into the molecular determinants of thermal stability in halohydrin dehalogenase HheD2.

Project: NetMoDEzyme

Updated at: 27-04-2024

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Project acronym NetMoDEzyme

Enzyme Conformation Influences the Performance of Lipase-powered Nanomotors

Project: NetMoDEzyme

Updated at: 27-04-2024

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Project acronym NetMoDEzyme

Exploring the Conversion of a d -Sialic Acid Aldolase into a l -KDO Aldolase

Project: NetMoDEzyme

Updated at: 27-04-2024

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Project acronym NetMoDEzyme

Regio‐ and Stereoselective Steroid Hydroxylation at C7 by Cytochrome P450 Monooxygenase Mutants

Project: NetMoDEzyme

Updated at: 27-04-2024

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Project acronym NetMoDEzyme

Intrinsic enzymatic properties modulate the self-propulsion of micromotors

Project: NetMoDEzyme

Updated at: 27-04-2024

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Project acronym NetMoDEzyme

Conformational Landscapes of Halohydrin Dehalogenases and Their Accessible Active Site Tunnels

Project: NetMoDEzyme

Updated at: 27-04-2024

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Project acronym NetMoDEzyme

Resources

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Biocatalysis

Synthesis, In Vitro Profiling, and In Vivo Evaluation of Benzohomoadamantane-Based Ureas for Visceral Pain: A New Indica...

Inducing high activity of a thermophilic enzyme at ambient temperatures by directed evolution

Deciphering the Allosterically Driven Conformational Ensemble in Tryptophan Synthase Evolution

Exploring the origins of selectivity in soluble epoxide hydrolase from Bacillus megaterium

Exploring the reversal of enantioselectivity on a zinc-dependent alcohol dehydrogenase

In Silico Identification and Experimental Validation of Distal Activity-Enhancing Mutations in Tryptophan Synthase.

Role of Conformational Dynamics in the Evolution of Retro-Aldolase Activity

Computational tools for the evaluation of laboratory-engineered biocatalysts

The challenge of predicting distal active site mutations in computational enzyme design

Mutational Analysis of Linalool Dehydratase Isomerase Suggests That Alcohol and Alkene Transformations Are Catalyzed Usi...

Pervasive cooperative mutational effects on multiple catalytic enzyme traits emerge via long-range conformational dynami...

Estimating conformational heterogeneity of tryptophan synthase with a template-based Alphafold2 approach

2-Oxaadamant-1-yl Ureas as Soluble Epoxide Hydrolase Inhibitors: In Vivo Evaluation in a Murine Model of Acute Pancreati...

Hidden Conformations in Aspergillus niger Monoamine Oxidase are Key for Catalytic Efficiency

p38γ is essential for cell cycle progression and liver tumorigenesis

SBMOpenMM: A Builder of Structure-Based Models for OpenMM.

Epoxide Hydrolase Conformational Heterogeneity for the Resolution of Bulky Pharmacologically Relevant Epoxide Substrates

Role of conformational dynamics in the evolution of novel enzyme function

Time Evolution of the Millisecond Allosteric Activation of Imidazole Glycerol Phosphate Synthase

Periodic Reporting for period 5 - NetMoDEzyme (Network models for the computational design of proficient enzymes)

Discovery and in Vivo Proof of Concept of a Highly Potent Dual Inhibitor of Soluble Epoxide Hydrolase and Acetylcholines...

In Vivo Selection for Formate Dehydrogenases with High Efficiency and Specificity toward NADP +

From the Design to the In Vivo Evaluation of Benzohomoadamantane-Derived Soluble Epoxide Hydrolase Inhibitors for the Tr...

Insights into the molecular determinants of thermal stability in halohydrin dehalogenase HheD2.

Enzyme Conformation Influences the Performance of Lipase-powered Nanomotors

Exploring the Conversion of a d -Sialic Acid Aldolase into a l -KDO Aldolase

Regio‐ and Stereoselective Steroid Hydroxylation at C7 by Cytochrome P450 Monooxygenase Mutants

Intrinsic enzymatic properties modulate the self-propulsion of micromotors

Conformational Landscapes of Halohydrin Dehalogenases and Their Accessible Active Site Tunnels