ERD

Supersaturated lipid-based drug delivery systems – exploring impact of lipid composition type and drug properties on s...

Project: PEARRL

Updated at: 28-04-2024

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Project acronym PEARRL

On the Usefulness of Two Small-Scale In Vitro Setups in the Evaluation of Luminal Precipitation of Lipophilic Weak Bases...

Project: PEARRL

Updated at: 28-04-2024

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Project acronym PEARRL

The mechanisms of pharmacokinetic food-drug interactions – A perspective from the UNGAP group

Project: PEARRL

Updated at: 28-04-2024

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Project acronym PEARRL

Combining biorelevant in vitro and in silico tools to investigate the in vivo performance of the amorphous solid dispers...

Project: PEARRL

Updated at: 28-04-2024

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Project acronym PEARRL

Disposition of two highly permeable drugs in the upper gastrointestinal lumen of healthy adults after a standard high-ca...

Project: PEARRL

Updated at: 28-04-2024

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Project acronym PEARRL

Polyelectrolytes in Hot Melt Extrusion: A Combined Solvent-Based and Interacting Additive Technique for Solid Dispersion...

Project: PEARRL

Updated at: 28-04-2024

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Project acronym PEARRL

On the Design of Food Effect Studies in Adults for Extrapolating Oral Drug Absorption Data to Infants: an Exploratory St...

Project: PEARRL

Updated at: 28-04-2024

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Project acronym PEARRL

Measuring pH and Buffer Capacity in Fluids Aspirated from the Fasted Upper Gastrointestinal Tract of Healthy Adults

Project: PEARRL

Updated at: 28-04-2024

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Project acronym PEARRL

Broadband Diffusing Wave Spectroscopy Reveals Microstructuring of Polymer–Drug System

Project: PEARRL

Updated at: 28-04-2024

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Project acronym PEARRL

Exploring impact of supersaturated lipid-based drug delivery systems of celecoxib on in vitro permeation across Permeapa...

Project: PEARRL

Updated at: 28-04-2024

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Project acronym PEARRL

Publications on in silico PBPK models for predict in vivo performance of bio-enabling formulations

Project: PEARRL

Updated at: 28-04-2024

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Project acronym PEARRL

White paper on ‘Opportunities for Regulatory Bio-waivers using integrated PBPK/PD approaches.

Project: PEARRL

Updated at: 28-04-2024

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Project acronym PEARRL

The impact of food intake on the luminal environment and performance of oral drug products with a view to in vitro and ...

Project: PEARRL

Updated at: 28-04-2024

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Project acronym PEARRL

A Novel Rheological Method to Assess Drug-Polymer Interactions Regarding Miscibility and Crystallization of Drug in Amor...

Project: PEARRL

Updated at: 28-04-2024

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Project acronym PEARRL

Establishing virtual bioequivalence and clinically relevant specifications using in vitro biorelevant dissolution testin...

Project: PEARRL

Updated at: 28-04-2024

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Project acronym PEARRL

Incorporation of HPMCAS during loading of glibenclamide onto mesoporous silica improves dissolution and inhibits precipi...

Project: PEARRL

Updated at: 28-04-2024

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Project acronym PEARRL

In‐vitro–in‐silico investigation of the negative food effect of zolpidem when administered as immediate‐release ...

Project: PEARRL

Updated at: 28-04-2024

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Project acronym PEARRL

The pig as a preclinical model for predicting oral bioavailability and in vivo performance of pharmaceutical oral dosag...

Project: PEARRL

Updated at: 28-04-2024

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Project acronym PEARRL

A Novel In Silico Screening Protocol For The Selection Of Optimized Precipitation Inhibitor Systems For Supersaturable F...

Project: PEARRL

Updated at: 28-04-2024

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Project acronym PEARRL

Exploring the Impact of Surfactant Type and Digestion: Highly Digestible Surfactants Improve Oral Bioavailability of Nil...

Project: PEARRL

Updated at: 28-04-2024

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Project acronym PEARRL

Application of the solubility parameter concept to assist with oral delivery of poorly water-soluble drugs - a PEARRL re...

Project: PEARRL

Updated at: 28-04-2024

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Project acronym PEARRL

Biopharmaceutical considerations in paediatrics with a view to the evaluation of orally administered drug products - a P...

Project: PEARRL

Updated at: 28-04-2024

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Project acronym PEARRL

In vitro methods to assess drug precipitation in the fasted small intestine - a PEARRL review

Project: PEARRL

Updated at: 28-04-2024

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Project acronym PEARRL

Exploring gastric emptying rate in mini-pigs: Effect of food type and pre-dosing of metoclopramide

Project: PEARRL

Updated at: 28-04-2024

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Project acronym PEARRL

Food for thought: formulating away the food effect - a PEARRL review

Project: PEARRL

Updated at: 28-04-2024

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Project acronym PEARRL

In Vitro Modelling Of Propranolol Immediate Release And Extended Release Formulations Using A Three Chamber Dissolution ...

Project: PEARRL

Updated at: 28-04-2024

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Project acronym PEARRL

Towards a better understanding of solid dispersions in aqueous environment by a fluorescence quenching approach

Project: PEARRL

Updated at: 28-04-2024

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Project acronym PEARRL

Modified Polymer Matrix in Pharmaceutical Hot Melt Extrusion by Molecular Interactions with a Carboxylic Coformer

Project: PEARRL

Updated at: 28-04-2024

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Project acronym PEARRL

Application of the relationship between pharmacokinetics and pharmacodynamics in drug development and therapeutic equiva...

Project: PEARRL

Updated at: 28-04-2024

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Project acronym PEARRL

Toward the establishment of a standardized pre-clinical porcine model to predict food effects – Case studies on fenofi...

Project: PEARRL

Updated at: 28-04-2024

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Project acronym PEARRL

Resources

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Supersaturated lipid-based drug delivery systems – exploring impact of lipid composition type and drug properties on s...

On the Usefulness of Two Small-Scale In Vitro Setups in the Evaluation of Luminal Precipitation of Lipophilic Weak Bases...

The mechanisms of pharmacokinetic food-drug interactions – A perspective from the UNGAP group

Combining biorelevant in vitro and in silico tools to investigate the in vivo performance of the amorphous solid dispers...

Disposition of two highly permeable drugs in the upper gastrointestinal lumen of healthy adults after a standard high-ca...

Polyelectrolytes in Hot Melt Extrusion: A Combined Solvent-Based and Interacting Additive Technique for Solid Dispersion...

On the Design of Food Effect Studies in Adults for Extrapolating Oral Drug Absorption Data to Infants: an Exploratory St...

Measuring pH and Buffer Capacity in Fluids Aspirated from the Fasted Upper Gastrointestinal Tract of Healthy Adults

Broadband Diffusing Wave Spectroscopy Reveals Microstructuring of Polymer–Drug System

Exploring impact of supersaturated lipid-based drug delivery systems of celecoxib on in vitro permeation across Permeapa...

Publications on in silico PBPK models for predict in vivo performance of bio-enabling formulations

White paper on ‘Opportunities for Regulatory Bio-waivers using integrated PBPK/PD approaches.

The impact of food intake on the luminal environment and performance of oral drug products with a view to in vitro and ...

A Novel Rheological Method to Assess Drug-Polymer Interactions Regarding Miscibility and Crystallization of Drug in Amor...

Establishing virtual bioequivalence and clinically relevant specifications using in vitro biorelevant dissolution testin...

Incorporation of HPMCAS during loading of glibenclamide onto mesoporous silica improves dissolution and inhibits precipi...

In‐vitro–in‐silico investigation of the negative food effect of zolpidem when administered as immediate‐release ...

The pig as a preclinical model for predicting oral bioavailability and in vivo performance of pharmaceutical oral dosag...

A Novel In Silico Screening Protocol For The Selection Of Optimized Precipitation Inhibitor Systems For Supersaturable F...

Exploring the Impact of Surfactant Type and Digestion: Highly Digestible Surfactants Improve Oral Bioavailability of Nil...

Application of the solubility parameter concept to assist with oral delivery of poorly water-soluble drugs - a PEARRL re...

Biopharmaceutical considerations in paediatrics with a view to the evaluation of orally administered drug products - a P...

In vitro methods to assess drug precipitation in the fasted small intestine - a PEARRL review

Exploring gastric emptying rate in mini-pigs: Effect of food type and pre-dosing of metoclopramide

Food for thought: formulating away the food effect - a PEARRL review

In Vitro Modelling Of Propranolol Immediate Release And Extended Release Formulations Using A Three Chamber Dissolution ...

Towards a better understanding of solid dispersions in aqueous environment by a fluorescence quenching approach

Modified Polymer Matrix in Pharmaceutical Hot Melt Extrusion by Molecular Interactions with a Carboxylic Coformer

Application of the relationship between pharmacokinetics and pharmacodynamics in drug development and therapeutic equiva...

Toward the establishment of a standardized pre-clinical porcine model to predict food effects – Case studies on fenofi...