ERD

Site selective 18F-Labeling of proteins eg AnnexinV, MCP1/CCL5, BACE1, GSM, APP, Tau

Project: FLUDD

Updated at: 28-04-2024

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Project acronym FLUDD

Selection and synthesis of best fragment- lead candidates for medicinal chemistry

Project: FLUDD

Updated at: 28-04-2024

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Project acronym FLUDD

Methods based on CH functionalization to 18F-label new 18F-chemotypes (eg (hetero)arylCHF2)

Project: FLUDD

Updated at: 28-04-2024

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Project acronym FLUDD

Defense of DPhil Thesis (Oxford)

Project: FLUDD

Updated at: 28-04-2024

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Project acronym FLUDD

Methods for site selective 18F-labeling of proteins

Project: FLUDD

Updated at: 28-04-2024

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Project acronym FLUDD

Organophotoredox Hydrodefluorination of Trifluoromethylarenes with Translational Applicability to Drug Discovery

Project: FLUDD

Updated at: 28-04-2024

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Project acronym FLUDD

Hydrogen Bonding Phase-Transfer Catalysis with Ionic Reactants: Enantioselective Synthesis of γ-Fluoroamines

Project: FLUDD

Updated at: 28-04-2024

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Project acronym FLUDD

Hydrosulfonylation of Alkenes with Sulfonyl Chlorides under Visible Light Activation

Project: FLUDD

Updated at: 28-04-2024

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Project acronym FLUDD

Metabolic studies and preclinical evaluation of priority 19/18F-biomolecules

Project: FLUDD

Updated at: 28-04-2024

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Project acronym FLUDD

Methods based on [18F][:CF2] carbene radiochemistry to label 18F-arylOCHF2 and 18F-arylSCHF2

Project: FLUDD

Updated at: 28-04-2024

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Project acronym FLUDD

Catalytic fluorocyclization of alkenes and alkynes towards thiazoles and thiazines

Project: FLUDD

Updated at: 28-04-2024

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Project acronym FLUDD

Light-driven post-translational installation of reactive protein side chains

Project: FLUDD

Updated at: 28-04-2024

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Project acronym FLUDD

Hydrochlorofluoromethylation of unactivated alkenes with chlorofluoroacetic acid

Project: FLUDD

Updated at: 28-04-2024

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Project acronym FLUDD

Silyl Radical-Mediated Activation of Sulfamoyl Chlorides Enables Direct Access to Aliphatic Sulfonamides from Alkenes

Project: FLUDD

Updated at: 28-04-2024

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Project acronym FLUDD

Hydrodifluoromethylation of Alkenes with Difluoroacetic Acid

Project: FLUDD

Updated at: 28-04-2024

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Project acronym FLUDD

Metabolic studies and preclinical evaluation of priority 19/18F-molecules

Project: FLUDD

Updated at: 28-04-2024

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Project acronym FLUDD

18F-Labeling of cyclobutanes, bicycles, spirocycles, oxetanes, thietanes, azetidines, thiazines and thiazoles

Project: FLUDD

Updated at: 28-04-2024

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Project acronym FLUDD

Dissemination of main results throughout the consortium and outside (oral and poster presentations) (eg International co...

Project: FLUDD

Updated at: 28-04-2024

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Project acronym FLUDD

Workshops and (inter)national conferences

Project: FLUDD

Updated at: 28-04-2024

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Project acronym FLUDD

Improvement of employability

Project: FLUDD

Updated at: 28-04-2024

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Project acronym FLUDD

Easy Access to Aliphatic Sulfonamides using Sulfamoyl Chlorides Under Visible Light Activation

Project: FLUDD

Updated at: 28-04-2024

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Project acronym FLUDD

Catalytic fluorination via CH functionalization of cyclobutanes, bicycles, spirocycles, oxetanes, thietanes and azetidin...

Project: FLUDD

Updated at: 28-04-2024

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Project acronym FLUDD

Production of TB 18F-probe under GMP conditions

Project: FLUDD

Updated at: 28-04-2024

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Project acronym FLUDD

Patents, research and review publications, assistance for creation of start-ups and incubation

Project: FLUDD

Updated at: 28-04-2024

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Project acronym FLUDD

Public Website, Press release, Outreach, Open days, Embassy

Project: FLUDD

Updated at: 28-04-2024

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Project acronym FLUDD

(Pre)clinical evaluation of TB 18F-probe

Project: FLUDD

Updated at: 28-04-2024

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Project acronym FLUDD

ESR recruitment process

Project: FLUDD

Updated at: 28-04-2024

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Project acronym FLUDD

Synthesis of 18F-carbohydrate probe for TB

Project: FLUDD

Updated at: 28-04-2024

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Project acronym FLUDD

FLUDD Schools

Project: FLUDD

Updated at: 28-04-2024

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Project acronym FLUDD

Periodic Reporting for period 2 - FLUDD (Late Stage Fluorination and its Applications to Drug Discovery)

Project: FLUDD

Updated at: 28-04-2024

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Project acronym FLUDD

Resources

Selected filters:

Site selective 18F-Labeling of proteins eg AnnexinV, MCP1/CCL5, BACE1, GSM, APP, Tau

Selection and synthesis of best fragment- lead candidates for medicinal chemistry

Methods based on CH functionalization to 18F-label new 18F-chemotypes (eg (hetero)arylCHF2)

Defense of DPhil Thesis (Oxford)

Methods for site selective 18F-labeling of proteins

Organophotoredox Hydrodefluorination of Trifluoromethylarenes with Translational Applicability to Drug Discovery

Hydrogen Bonding Phase-Transfer Catalysis with Ionic Reactants: Enantioselective Synthesis of γ-Fluoroamines

Hydrosulfonylation of Alkenes with Sulfonyl Chlorides under Visible Light Activation

Metabolic studies and preclinical evaluation of priority 19/18F-biomolecules

Methods based on [18F][:CF2] carbene radiochemistry to label 18F-arylOCHF2 and 18F-arylSCHF2

Catalytic fluorocyclization of alkenes and alkynes towards thiazoles and thiazines

Light-driven post-translational installation of reactive protein side chains

Hydrochlorofluoromethylation of unactivated alkenes with chlorofluoroacetic acid

Silyl Radical-Mediated Activation of Sulfamoyl Chlorides Enables Direct Access to Aliphatic Sulfonamides from Alkenes

Hydrodifluoromethylation of Alkenes with Difluoroacetic Acid

Metabolic studies and preclinical evaluation of priority 19/18F-molecules

18F-Labeling of cyclobutanes, bicycles, spirocycles, oxetanes, thietanes, azetidines, thiazines and thiazoles

Dissemination of main results throughout the consortium and outside (oral and poster presentations) (eg International co...

Workshops and (inter)national conferences

Improvement of employability

Easy Access to Aliphatic Sulfonamides using Sulfamoyl Chlorides Under Visible Light Activation

Catalytic fluorination via CH functionalization of cyclobutanes, bicycles, spirocycles, oxetanes, thietanes and azetidin...

Production of TB 18F-probe under GMP conditions

Patents, research and review publications, assistance for creation of start-ups and incubation

Public Website, Press release, Outreach, Open days, Embassy

(Pre)clinical evaluation of TB 18F-probe

ESR recruitment process

Synthesis of 18F-carbohydrate probe for TB

FLUDD Schools

Periodic Reporting for period 2 - FLUDD (Late Stage Fluorination and its Applications to Drug Discovery)