ERD

Structural characterization of a novel GPVI-nanobody complex reveals a biologically active domain-swapped GPVI dimer

Project: TAPAS

Updated at: 28-04-2024

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Project acronym TAPAS

Multiparameter Evaluation of the Platelet-Inhibitory Effects of Tyrosine Kinase Inhibitors Used for Cancer Treatment

Project: TAPAS

Updated at: 28-04-2024

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Project acronym TAPAS

Nonredundant Roles of Platelet Glycoprotein VI and Integrin αIIbβ3 in Fibrin-Mediated Microthrombus Formation

Project: TAPAS

Updated at: 28-04-2024

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Project acronym TAPAS

Ultra-high-throughput Ca2+ assay in platelets to distinguish ITAM-linked and G-protein-coupled receptor activation

Project: TAPAS

Updated at: 28-04-2024

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Project acronym TAPAS

Periodic Reporting for period 2 - TAPAS (TArgeting Platelet Adhesion receptors in thrombosiS)

Project: TAPAS

Updated at: 28-04-2024

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Project acronym TAPAS

Organisation of Training Workshops and Conferences

Project: TAPAS

Updated at: 28-04-2024

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Project acronym TAPAS

Evidence that GPVI is Expressed as a Mixture of Monomers and Dimers, and that the D2 Domain is not Essential for GPVI Ac...

Project: TAPAS

Updated at: 28-04-2024

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Project acronym TAPAS

Katacine is a new ligand of CLEC-2 that acts as a platelet agonist

Project: TAPAS

Updated at: 28-04-2024

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Project acronym TAPAS

Tyrosine Kinase Inhibitor Sunitinib Delays Platelet-Induced Coagulation: Additive Effects of Aspirin

Project: TAPAS

Updated at: 28-04-2024

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Project acronym TAPAS

Organisation of second European Summer School

Project: TAPAS

Updated at: 28-04-2024

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Project acronym TAPAS

Thrombo-Inflammation in Cardiovascular Disease: An Expert Consensus Document from the Third Maastricht Consensus Confere...

Project: TAPAS

Updated at: 28-04-2024

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Project acronym TAPAS

Whole Blood Based Multiparameter Assessment of Thrombus Formation in Standard Microfluidic Devices to Proxy In Vivo Haem...

Project: TAPAS

Updated at: 28-04-2024

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Project acronym TAPAS

A Comprehensive Tyrosine Phosphoproteomic Analysis Reveals Novel Components of the Platelet CLEC-2 Signaling Cascade

Project: TAPAS

Updated at: 28-04-2024

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Project acronym TAPAS

Localised endothelial‐based control of platelet aggregation and coagulation under flow: a proof‐of‐principle vesse...

Project: TAPAS

Updated at: 28-04-2024

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Project acronym TAPAS

Temporal Roles of Platelet and Coagulation Pathways in Collagen- and Tissue Factor-Induced Thrombus Formation

Project: TAPAS

Updated at: 28-04-2024

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Project acronym TAPAS

Setup of TAPAS website (updates every 6 months)

Project: TAPAS

Updated at: 28-04-2024

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Project acronym TAPAS

15 PhD theses with awarded EJD degrees

Project: TAPAS

Updated at: 28-04-2024

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Project acronym TAPAS

A large-scale histological investigation gives insight into the structure of ischemic stroke thrombi

Project: TAPAS

Updated at: 28-04-2024

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Project acronym TAPAS

Clonal hematopoietic mutations linked to platelet traits and the risk of thrombosis or bleeding

Project: TAPAS

Updated at: 28-04-2024

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Project acronym TAPAS

Assessment of a complete and classified platelet proteome from genome-wide transcripts of human platelets and megakaryoc...

Project: TAPAS

Updated at: 28-04-2024

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Project acronym TAPAS

Interspecies differences in protein expression do not impact the spatiotemporal regulation of GPVI mediated activation

Project: TAPAS

Updated at: 28-04-2024

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Project acronym TAPAS

Role of Platelet Glycoprotein VI and Tyrosine Kinase Syk in Thrombus Formation on Collagen-Like Surfaces

Project: TAPAS

Updated at: 28-04-2024

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Project acronym TAPAS

Overcoming challenges in developing small molecule inhibitors for GPVI and CLEC-2

Project: TAPAS

Updated at: 28-04-2024

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Project acronym TAPAS

Recruitment of 15 ESRs (with statistics of applications)

Project: TAPAS

Updated at: 28-04-2024

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Project acronym TAPAS

Dissemination and Outreach activity plan completed

Project: TAPAS

Updated at: 28-04-2024

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Project acronym TAPAS

Organsation of Training Workshops and Conferences

Project: TAPAS

Updated at: 28-04-2024

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Project acronym TAPAS

Organisation of first European Summer School

Project: TAPAS

Updated at: 28-04-2024

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Project acronym TAPAS

Multiparameter microfluidics assay of thrombus formation reveals increased sensitivity to contraction and antiplatelet a...

Project: TAPAS

Updated at: 28-04-2024

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Project acronym TAPAS

Progress report

Project: TAPAS

Updated at: 28-04-2024

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Project acronym TAPAS

Rac Inhibition Causes Impaired GPVI Signalling in Human Platelets through GPVI Shedding and Reduction in PLCγ2 Phosphor...

Project: TAPAS

Updated at: 28-04-2024

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Project acronym TAPAS

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Structural characterization of a novel GPVI-nanobody complex reveals a biologically active domain-swapped GPVI dimer

Multiparameter Evaluation of the Platelet-Inhibitory Effects of Tyrosine Kinase Inhibitors Used for Cancer Treatment

Nonredundant Roles of Platelet Glycoprotein VI and Integrin αIIbβ3 in Fibrin-Mediated Microthrombus Formation

Ultra-high-throughput Ca2+ assay in platelets to distinguish ITAM-linked and G-protein-coupled receptor activation

Periodic Reporting for period 2 - TAPAS (TArgeting Platelet Adhesion receptors in thrombosiS)

Organisation of Training Workshops and Conferences

Evidence that GPVI is Expressed as a Mixture of Monomers and Dimers, and that the D2 Domain is not Essential for GPVI Ac...

Katacine is a new ligand of CLEC-2 that acts as a platelet agonist

Tyrosine Kinase Inhibitor Sunitinib Delays Platelet-Induced Coagulation: Additive Effects of Aspirin

Organisation of second European Summer School

Thrombo-Inflammation in Cardiovascular Disease: An Expert Consensus Document from the Third Maastricht Consensus Confere...

Whole Blood Based Multiparameter Assessment of Thrombus Formation in Standard Microfluidic Devices to Proxy In Vivo Haem...

A Comprehensive Tyrosine Phosphoproteomic Analysis Reveals Novel Components of the Platelet CLEC-2 Signaling Cascade

Localised endothelial‐based control of platelet aggregation and coagulation under flow: a proof‐of‐principle vesse...

Temporal Roles of Platelet and Coagulation Pathways in Collagen- and Tissue Factor-Induced Thrombus Formation

Setup of TAPAS website (updates every 6 months)

15 PhD theses with awarded EJD degrees

A large-scale histological investigation gives insight into the structure of ischemic stroke thrombi

Clonal hematopoietic mutations linked to platelet traits and the risk of thrombosis or bleeding

Assessment of a complete and classified platelet proteome from genome-wide transcripts of human platelets and megakaryoc...

Interspecies differences in protein expression do not impact the spatiotemporal regulation of GPVI mediated activation

Role of Platelet Glycoprotein VI and Tyrosine Kinase Syk in Thrombus Formation on Collagen-Like Surfaces

Overcoming challenges in developing small molecule inhibitors for GPVI and CLEC-2

Recruitment of 15 ESRs (with statistics of applications)

Dissemination and Outreach activity plan completed

Organsation of Training Workshops and Conferences

Organisation of first European Summer School

Multiparameter microfluidics assay of thrombus formation reveals increased sensitivity to contraction and antiplatelet a...

Progress report

Rac Inhibition Causes Impaired GPVI Signalling in Human Platelets through GPVI Shedding and Reduction in PLCγ2 Phosphor...