ERD

Outlier response to anti-PD1 in uveal melanoma reveals germline MBD4 mutations in hypermutated tumors

Project: UM Cure 2020

Updated at: 29-04-2024

Show more information

Project acronym UM Cure 2020

New Therapeutic Approach for Targeting Hippo Signalling Pathway

Project: UM Cure 2020

Updated at: 29-04-2024

Show more information

Project acronym UM Cure 2020

A novel circulating tumour cell-derived xenograft (CDX) model to investigate uveal melanoma metastasis

Project: UM Cure 2020

Updated at: 29-04-2024

Show more information

Project acronym UM Cure 2020

Kick-off meeting

Project: UM Cure 2020

Updated at: 29-04-2024

Show more information

Project acronym UM Cure 2020

Preclinical evaluation of drug combinations identifies co-inhibition of Bcl-2/XL/W and MDM2 as a potential therapy in uv...

Project: UM Cure 2020

Updated at: 29-04-2024

Show more information

Project acronym UM Cure 2020

Aqueous Humor Biomarkers Identify Three Prognostic Groups in Uveal Melanoma

Project: UM Cure 2020

Updated at: 29-04-2024

Show more information

Project acronym UM Cure 2020

Ischemia Is Related to Tumour Genetics in Uveal Melanoma

Project: UM Cure 2020

Updated at: 29-04-2024

Show more information

Project acronym UM Cure 2020

Evolutionary routes in metastatic uveal melanomas depend on MBD4 alterations.

Project: UM Cure 2020

Updated at: 29-04-2024

Show more information

Project acronym UM Cure 2020

Do GNAQ and GNA11 Differentially Affect Inflammation and HLA Expression in Uveal Melanoma?

Project: UM Cure 2020

Updated at: 29-04-2024

Show more information

Project acronym UM Cure 2020

Soluble HLA in the Aqueous Humour of Uveal Melanoma Is Associated with Unfavourable Tumour Characteristics

Project: UM Cure 2020

Updated at: 29-04-2024

Show more information

Project acronym UM Cure 2020

HLA Expression in Uveal Melanoma: An Indicator of Malignancy and a Modifiable Immunological Target

Project: UM Cure 2020

Updated at: 29-04-2024

Show more information

Project acronym UM Cure 2020

So Close, yet so Far: Discrepancies between Uveal and Other Melanomas. A Position Paper from UM Cure 2020

Project: UM Cure 2020

Updated at: 29-04-2024

Show more information

Project acronym UM Cure 2020

Loss of BAP1 Is Associated with Upregulation of the NFkB Pathway and Increased HLA Class I Expression in Uveal Melanoma

Project: UM Cure 2020

Updated at: 29-04-2024

Show more information

Project acronym UM Cure 2020

Tumour Angiogenesis in Uveal Melanoma Is Related to Genetic Evolution

Project: UM Cure 2020

Updated at: 29-04-2024

Show more information

Project acronym UM Cure 2020

Differential Expression of DNA Repair Genes in Prognostically-Favorable versus Unfavorable Uveal Melanoma

Project: UM Cure 2020

Updated at: 29-04-2024

Show more information

Project acronym UM Cure 2020

Emerging Therapeutic Opportunities Based on Current Knowledge of Uveal Melanoma Biology

Project: UM Cure 2020

Updated at: 29-04-2024

Show more information

Project acronym UM Cure 2020

Automated in vivo screen in zebrafish identifies Clotrimazole as targeting a metabolic vulnerability in a melanoma model

Project: UM Cure 2020

Updated at: 29-04-2024

Show more information

Project acronym UM Cure 2020

The Zebrafish as an Emerging Model to Study DNA Damage in Aging, Cancer and Other Diseases

Project: UM Cure 2020

Updated at: 29-04-2024

Show more information

Project acronym UM Cure 2020

Functional and conformational impact of cancer-associated SF3B1 mutations depends on the position and the charge of amin...

Project: UM Cure 2020

Updated at: 29-04-2024

Show more information

Project acronym UM Cure 2020

Involvement of mutant and wild-type CYSLTR2 in the development and progression of uveal nevi and melanoma

Project: UM Cure 2020

Updated at: 29-04-2024

Show more information

Project acronym UM Cure 2020

Genetic alterations of SUGP1 mimic mutant-SF3B1 splice pattern in lung adenocarcinoma and other cancers

Project: UM Cure 2020

Updated at: 29-04-2024

Show more information

Project acronym UM Cure 2020

Ortho- and Ectopic Zebrafish Xeno-Engraftment of Ocular Melanoma to Recapitulate Primary Tumor and Experimental Metastas...

Project: UM Cure 2020

Updated at: 29-04-2024

Show more information

Project acronym UM Cure 2020

Quantification of DNA methylation independent of sodium bisulfite conversion using methylation‐sensitive restriction e...

Project: UM Cure 2020

Updated at: 29-04-2024

Show more information

Project acronym UM Cure 2020

Splicing patterns in SF3B1 mutated uveal melanoma generate shared immunogenic tumor-specific neo-epitopes

Project: UM Cure 2020

Updated at: 29-04-2024

Show more information

Project acronym UM Cure 2020

Different Pigmentation Risk Loci for High-Risk Monosomy 3 and Low-Risk Disomy 3 Uveal Melanomas

Project: UM Cure 2020

Updated at: 29-04-2024

Show more information

Project acronym UM Cure 2020

Sunglasses to hide behind may also prevent melanoma of the eyes

Project: UM Cure 2020

Updated at: 29-04-2024

Show more information

Project acronym UM Cure 2020

European guidelines for UM patient management and dissemination status

Project: UM Cure 2020

Updated at: 29-04-2024

Show more information

Project acronym UM Cure 2020

Novel Treatments of Uveal Melanoma Identified with a Synthetic Lethal CRISPR/Cas9 Screen

Project: UM Cure 2020

Updated at: 29-04-2024

Show more information

Project acronym UM Cure 2020

Preclinical Evaluation of Trabectedin in Combination With Targeted Inhibitors for Treatment of Metastatic Uveal Melanoma

Project: UM Cure 2020

Updated at: 29-04-2024

Show more information

Project acronym UM Cure 2020

Periodic Reporting for period 4 - UM Cure 2020 (New therapies for uveal melanoma)

Project: UM Cure 2020

Updated at: 28-07-2022

Show more information

Project acronym UM Cure 2020

Resources

Selected filters:

Outlier response to anti-PD1 in uveal melanoma reveals germline MBD4 mutations in hypermutated tumors

New Therapeutic Approach for Targeting Hippo Signalling Pathway

A novel circulating tumour cell-derived xenograft (CDX) model to investigate uveal melanoma metastasis

Kick-off meeting

Preclinical evaluation of drug combinations identifies co-inhibition of Bcl-2/XL/W and MDM2 as a potential therapy in uv...

Aqueous Humor Biomarkers Identify Three Prognostic Groups in Uveal Melanoma

Ischemia Is Related to Tumour Genetics in Uveal Melanoma

Evolutionary routes in metastatic uveal melanomas depend on MBD4 alterations.

Do GNAQ and GNA11 Differentially Affect Inflammation and HLA Expression in Uveal Melanoma?

Soluble HLA in the Aqueous Humour of Uveal Melanoma Is Associated with Unfavourable Tumour Characteristics

HLA Expression in Uveal Melanoma: An Indicator of Malignancy and a Modifiable Immunological Target

So Close, yet so Far: Discrepancies between Uveal and Other Melanomas. A Position Paper from UM Cure 2020

Loss of BAP1 Is Associated with Upregulation of the NFkB Pathway and Increased HLA Class I Expression in Uveal Melanoma

Tumour Angiogenesis in Uveal Melanoma Is Related to Genetic Evolution

Differential Expression of DNA Repair Genes in Prognostically-Favorable versus Unfavorable Uveal Melanoma

Emerging Therapeutic Opportunities Based on Current Knowledge of Uveal Melanoma Biology

Automated in vivo screen in zebrafish identifies Clotrimazole as targeting a metabolic vulnerability in a melanoma model

The Zebrafish as an Emerging Model to Study DNA Damage in Aging, Cancer and Other Diseases

Functional and conformational impact of cancer-associated SF3B1 mutations depends on the position and the charge of amin...

Involvement of mutant and wild-type CYSLTR2 in the development and progression of uveal nevi and melanoma

Genetic alterations of SUGP1 mimic mutant-SF3B1 splice pattern in lung adenocarcinoma and other cancers

Ortho- and Ectopic Zebrafish Xeno-Engraftment of Ocular Melanoma to Recapitulate Primary Tumor and Experimental Metastas...

Quantification of DNA methylation independent of sodium bisulfite conversion using methylation‐sensitive restriction e...

Splicing patterns in SF3B1 mutated uveal melanoma generate shared immunogenic tumor-specific neo-epitopes

Different Pigmentation Risk Loci for High-Risk Monosomy 3 and Low-Risk Disomy 3 Uveal Melanomas

Sunglasses to hide behind may also prevent melanoma of the eyes

European guidelines for UM patient management and dissemination status

Novel Treatments of Uveal Melanoma Identified with a Synthetic Lethal CRISPR/Cas9 Screen

Preclinical Evaluation of Trabectedin in Combination With Targeted Inhibitors for Treatment of Metastatic Uveal Melanoma

Periodic Reporting for period 4 - UM Cure 2020 (New therapies for uveal melanoma)