ERD

Periodic Reporting for period 6 - ITCC-P4 (ITCC Pediatric Preclinical POC Platform – Sofia ref.: 116064)

Project: ITCC-P4

Updated at: 31-03-2024

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Project acronym ITCC-P4

Target actionability review to evaluate CDK4/6 as a therapeutic target in paediatric solid and brain tumours

Project: ITCC-P4

Updated at: 30-11-2023

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Project acronym ITCC-P4

Single-Cell RNA-Seq Reveals Cellular Hierarchies and Impaired Developmental Trajectories in Pediatric Ependymoma

Project: ITCC-P4

Updated at: 30-11-2023

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Project acronym ITCC-P4

TERT expression is susceptible to BRAF and ETS-factor inhibition in BRAFV600E/TERT promoter double-mutated glioma

Project: ITCC-P4

Updated at: 30-11-2023

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Project acronym ITCC-P4

Increased Anaplastic Lymphoma Kinase Activity Induces a Poorly Differentiated Thyroid Carcinoma in Mice

Project: ITCC-P4

Updated at: 30-11-2023

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Project acronym ITCC-P4

Synergistic activity of BET inhibitor MK-8628 and PLK inhibitor Volasertib in preclinical models of medulloblastoma

Project: ITCC-P4

Updated at: 30-11-2023

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Project acronym ITCC-P4

ROCK2 deprivation leads to the inhibition of tumor growth and metastatic potential in osteosarcoma cells through the mod...

Project: ITCC-P4

Updated at: 30-11-2023

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Project acronym ITCC-P4

International scientific symposium on : “Preclinicalevaluation in pediatric oncology drug development”

Project: ITCC-P4

Updated at: 30-11-2023

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Project acronym ITCC-P4

International consensus on minimum preclinical testing requirements for the development of innovative therapies for chil...

Project: ITCC-P4

Updated at: 30-11-2023

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Project acronym ITCC-P4

Systematic target actionability reviews of preclinical proof-of-concept papers to match targeted drugs to paediatric can...

Project: ITCC-P4

Updated at: 30-11-2023

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Project acronym ITCC-P4

Targeting fibroblast growth factor receptors to combat aggressive ependymoma

Project: ITCC-P4

Updated at: 30-11-2023

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Project acronym ITCC-P4

Prognostic value of patient-derived xenograft engraftment in pediatric sarcomas

Project: ITCC-P4

Updated at: 30-11-2023

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Project acronym ITCC-P4

Crossing Oceans: Preclinical Collaboration to Improve Pediatric Drug Development

Project: ITCC-P4

Updated at: 30-11-2023

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Project acronym ITCC-P4

Phenotypic profiling with a living biobank of primary rhabdomyosarcoma unravels disease heterogeneity and AKT sensitivit...

Project: ITCC-P4

Updated at: 30-11-2023

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Project acronym ITCC-P4

Final draft and Submission of a paper for publication

Project: ITCC-P4

Updated at: 30-11-2023

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Project acronym ITCC-P4

PCLN-05. A BIOBANK OF PATIENT-DERIVED MOLECULARLY CHARACTERIZED ORTHOTOPIC PEDIATRIC BRAIN TUMOR MODELS FOR PRECLINICAL ...

Project: ITCC-P4

Updated at: 30-11-2023

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Project acronym ITCC-P4

Small-Molecule Dual PLK1 and BRD4 Inhibitors are Active Against Preclinical Models of Pediatric Solid Tumors

Project: ITCC-P4

Updated at: 30-11-2023

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Project acronym ITCC-P4

A biobank of patient-derived pediatric brain tumor models

Project: ITCC-P4

Updated at: 30-11-2023

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Project acronym ITCC-P4

Integrated molecular characterization of patient-derived models reveals therapeutic strategies for treating CIC-DUX4 sar...

Project: ITCC-P4

Updated at: 30-11-2023

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Project acronym ITCC-P4

Target Actionability Review: a systematic evaluation of replication stress as a therapeutic target for pediatric solid m...

Project: ITCC-P4

Updated at: 30-11-2023

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Project acronym ITCC-P4

Ewing Sarcoma PDX Models

Project: ITCC-P4

Updated at: 30-11-2023

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Project acronym ITCC-P4

Molecular and preclinical evaluation of patient-derived orthotopic xenograft models of pediatric brain tumors

Project: ITCC-P4

Updated at: 30-11-2023

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Project acronym ITCC-P4

Resources

Selected filters:

Periodic Reporting for period 6 - ITCC-P4 (ITCC Pediatric Preclinical POC Platform – Sofia ref.: 116064)

Target actionability review to evaluate CDK4/6 as a therapeutic target in paediatric solid and brain tumours

Single-Cell RNA-Seq Reveals Cellular Hierarchies and Impaired Developmental Trajectories in Pediatric Ependymoma

TERT expression is susceptible to BRAF and ETS-factor inhibition in BRAFV600E/TERT promoter double-mutated glioma

Increased Anaplastic Lymphoma Kinase Activity Induces a Poorly Differentiated Thyroid Carcinoma in Mice

Synergistic activity of BET inhibitor MK-8628 and PLK inhibitor Volasertib in preclinical models of medulloblastoma

ROCK2 deprivation leads to the inhibition of tumor growth and metastatic potential in osteosarcoma cells through the mod...

International scientific symposium on : “Preclinicalevaluation in pediatric oncology drug development”

International consensus on minimum preclinical testing requirements for the development of innovative therapies for chil...

Systematic target actionability reviews of preclinical proof-of-concept papers to match targeted drugs to paediatric can...

Targeting fibroblast growth factor receptors to combat aggressive ependymoma

Prognostic value of patient-derived xenograft engraftment in pediatric sarcomas

Crossing Oceans: Preclinical Collaboration to Improve Pediatric Drug Development

Phenotypic profiling with a living biobank of primary rhabdomyosarcoma unravels disease heterogeneity and AKT sensitivit...

Final draft and Submission of a paper for publication

PCLN-05. A BIOBANK OF PATIENT-DERIVED MOLECULARLY CHARACTERIZED ORTHOTOPIC PEDIATRIC BRAIN TUMOR MODELS FOR PRECLINICAL ...

Small-Molecule Dual PLK1 and BRD4 Inhibitors are Active Against Preclinical Models of Pediatric Solid Tumors

A biobank of patient-derived pediatric brain tumor models

Integrated molecular characterization of patient-derived models reveals therapeutic strategies for treating CIC-DUX4 sar...

Target Actionability Review: a systematic evaluation of replication stress as a therapeutic target for pediatric solid m...

Ewing Sarcoma PDX Models

Molecular and preclinical evaluation of patient-derived orthotopic xenograft models of pediatric brain tumors