Resources
Restoration of T and B Cell Differentiation after RAG1 Gene Transfer in Human RAG1 Defective Hematopoietic Stem Cells
Project: RECOMB
Updated at: 01-05-2025
Advances in gene therapy for inborn errors of immunity
Project: RECOMB
Updated at: 01-05-2025
Gene therapy strategies for RAG1 deficiency: Challenges and breakthroughs
Project: RECOMB
Updated at: 01-05-2025
HyperIgE in hypomorphic recombination-activating gene defects
Project: RECOMB
Updated at: 01-05-2025
Partial correction of immunodeficiency by lentiviral vector gene therapy in mouse models carrying Rag1 hypomorphic mutat...
Project: RECOMB
Updated at: 01-05-2025
Utilizing epigenetic regulators to improve HSC-based lentiviral gene therapy
Project: RECOMB
Updated at: 01-05-2025
Innovative Cell-Based Therapies and Conditioning to Cure RAG Deficiency
Project: RECOMB
Updated at: 29-04-2024
Targeted Repair of p47-CGD in iPSCs by CRISPR/Cas9: Functional Correction without Cleavage in the Highly Homologous Pseu...
Project: RECOMB
Updated at: 29-04-2024
Preclinical Development of Autologous Hematopoietic Stem Cell-Based Gene Therapy for Immune Deficiencies: A Journey from...
Project: RECOMB
Updated at: 29-04-2024
Predicting genotoxicity of viral vectors for stem cell gene therapy using gene expression-based machine learning
Project: RECOMB
Updated at: 29-04-2024
A Small Key for a Heavy Door: Genetic Therapies for the Treatment of Hemoglobinopathies
Project: RECOMB
Updated at: 29-04-2024
Lentiviral Vector Gene Therapy in Rag1 Hypomorphic Mice: Treating Immunodeficiency in the Context of Immune Dysregulatio...
Project: RECOMB
Updated at: 29-04-2024
Efficacy assessment of lentiviral vector gene therapy in the immune dysregulated hypomorphic Rag1 mice
Project: RECOMB
Updated at: 29-04-2024
The quest for the holy grail: overcoming challenges in expanding human hematopoietic stem cells for clinical use.
Project: RECOMB
Updated at: 29-04-2024
RECOMB Website
Project: RECOMB
Updated at: 29-04-2024
A Large Cohort of RAG1/2-Deficient SCID PatientsāClinical, Immunological, and Prognostic Analysis
Project: RECOMB
Updated at: 29-04-2024
Successful Preclinical Development of Gene Therapy for Recombinase-Activating Gene-1-Deficient SCID
Project: RECOMB
Updated at: 29-04-2024
Use of Cell and Genome Modification Technologies to Generate Improved āOff-the-Shelfā CAR T and CAR NK Cells
Project: RECOMB
Updated at: 29-04-2024
Inflammation and Wnt Signaling: Target for Immunomodulatory Therapy?
Project: RECOMB
Updated at: 29-04-2024
Multi-omic analyses in immune cell development with lessons learned from T cell development.
Project: RECOMB
Updated at: 29-04-2024
A Novel Branched DNA-Based Flowcytometric Method for Single-Cell Characterization of Gene Therapy Products and Expressio...
Project: RECOMB
Updated at: 29-04-2024
An adequate human T cell repertoire from a single T cell progenitor: Lessons from an experiment of nature.
Project: RECOMB
Updated at: 29-04-2024
Genomic Engineering in Human Hematopoietic Stem Cells: Hype or Hope?
Project: RECOMB
Updated at: 29-04-2024
Single-cell immune profiling reveals thymus-seeding populations, T cell commitment, and multilineage development in the ...
Project: RECOMB
Updated at: 29-04-2024
Cell intrinsic regulation of external hematopoietic stem cell stress
Project: RECOMB
Updated at: 29-04-2024
Manufacturing Lentiviral Vector as Gene Therapy for RAG1-SCID
Project: RECOMB
Updated at: 29-04-2024
The recombinase activating genes: architects of immune diversity during lymphocyte development.
Project: RECOMB
Updated at: 29-04-2024
SIDUSĀ® technology for viral vector manufacturing
Project: RECOMB
Updated at: 29-04-2024
Periodic Reporting for period 4 - RECOMB (Stem-cell based gene therapy for recombination deficient SCID (RECOMB))
Project: RECOMB
Updated at: 29-04-2024