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Periodic Reporting for period 1 - TOX-Free (TOXicity assessment on neurons and cardiomyocytes by means of FluoRescence E...

Project: TOX-Free

Updated at: 27-04-2024

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Profiling of Human Neural Crest Chemoattractant Activity as a Replacement of Fetal Bovine Serum for In Vitro Chemotaxis ...

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Updated at: 27-04-2024

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G × E interactions as a basis for toxicological uncertainty

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Updated at: 27-04-2024

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Circulating (Poly)phenol Metabolites: Neuroprotection in a 3D Cell Model of Parkinson's Disease

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Updated at: 27-04-2024

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Long-term in vitro recording of cardiac action potentials on microelectrode arrays for chronic cardiotoxicity assessment

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Updated at: 27-04-2024

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Acute effects of the imidacloprid metabolite desnitro-imidacloprid on human nACh receptors relevant for neuronal signali...

Project: TOX-Free

Updated at: 27-04-2024

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Passive Recording of Bioelectrical Signals from Non-Excitable Cells by Fluorescent Mirroring

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Updated at: 27-04-2024

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Classification of Developmental Toxicants in a Human iPSC Transcriptomics-Based Test

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Updated at: 27-04-2024

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Direct recording of action potentials of cardiomyocytes through solution processed planar electrolyte-gated field-effect...

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A framework for chemical safety assessment incorporating new approach methodologies within REACH

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Updated at: 27-04-2024

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Probing ND7/23 neuronal cells before and after differentiation with SERS using Sharp-tipped Au nanopyramid arrays

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Updated at: 27-04-2024

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Establishment of a Human Cell-Based in Vitro Battery to Assess Developmental Neurotoxicity Hazard of Chemicals

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Updated at: 27-04-2024

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Specific Attenuation of Purinergic Signaling during Bortezomib-Induced Peripheral Neuropathy In Vitro

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Updated at: 27-04-2024

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On the usefulness of animals as a model system (part I): Overview of criteria and focus on robustness

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Updated at: 27-04-2024

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Report on the readout capabilities of VICE 1.0 with neurons

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Updated at: 27-04-2024

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High Accuracy Classification of Developmental Toxicants by In Vitro Tests of Human Neuroepithelial and Cardiomyoblast Di...

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Updated at: 27-04-2024

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Assay for evaluation of proarrhythmic effects of herbal products: Case study with 12 Evodia preparations

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Updated at: 27-04-2024

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Synuclein Family Members Prevent Membrane Damage by Counteracting α-Synuclein Aggregation.

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Updated at: 27-04-2024

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Analysis of health concerns not addressed by REACH for low tonnage chemicals and opportunities for new approach methodol...

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Dynamic Metabolic and Transcriptional Responses of Proteasome-Inhibited Neurons

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Updated at: 27-04-2024

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Distinct and Dynamic Transcriptome Adaptations of iPSC-Generated Astrocytes after Cytokine Stimulation

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Updated at: 27-04-2024

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Laser-Induced Action Potential-Like Measurements of Cardiomyocytes on Microelectrode Arrays for Increased Predictivity o...

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Updated at: 27-04-2024

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On the usefulness of animals as a model system (part II): Considering benefits within distinct use domains

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Updated at: 27-04-2024

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Generation of Human Nociceptor-Enriched Sensory Neurons for the Study of Pain-Related Dysfunctions

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Updated at: 27-04-2024

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Optimization of the TeraTox assay for preclinical teratogenicity assessment

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Updated at: 27-04-2024

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Periodic Reporting for period 1 - TOX-Free (TOXicity assessment on neurons and cardiomyocytes by means of FluoRescence E...

Profiling of Human Neural Crest Chemoattractant Activity as a Replacement of Fetal Bovine Serum for In Vitro Chemotaxis ...

G × E interactions as a basis for toxicological uncertainty

Circulating (Poly)phenol Metabolites: Neuroprotection in a 3D Cell Model of Parkinson's Disease

Long-term in vitro recording of cardiac action potentials on microelectrode arrays for chronic cardiotoxicity assessment

Acute effects of the imidacloprid metabolite desnitro-imidacloprid on human nACh receptors relevant for neuronal signali...

Passive Recording of Bioelectrical Signals from Non-Excitable Cells by Fluorescent Mirroring

Classification of Developmental Toxicants in a Human iPSC Transcriptomics-Based Test

Direct recording of action potentials of cardiomyocytes through solution processed planar electrolyte-gated field-effect...

A framework for chemical safety assessment incorporating new approach methodologies within REACH

Probing ND7/23 neuronal cells before and after differentiation with SERS using Sharp-tipped Au nanopyramid arrays

Establishment of a Human Cell-Based in Vitro Battery to Assess Developmental Neurotoxicity Hazard of Chemicals

Specific Attenuation of Purinergic Signaling during Bortezomib-Induced Peripheral Neuropathy In Vitro

On the usefulness of animals as a model system (part I): Overview of criteria and focus on robustness

Report on the readout capabilities of VICE 1.0 with neurons

High Accuracy Classification of Developmental Toxicants by In Vitro Tests of Human Neuroepithelial and Cardiomyoblast Di...

Assay for evaluation of proarrhythmic effects of herbal products: Case study with 12 Evodia preparations

Synuclein Family Members Prevent Membrane Damage by Counteracting α-Synuclein Aggregation.

Analysis of health concerns not addressed by REACH for low tonnage chemicals and opportunities for new approach methodol...

Dynamic Metabolic and Transcriptional Responses of Proteasome-Inhibited Neurons

Distinct and Dynamic Transcriptome Adaptations of iPSC-Generated Astrocytes after Cytokine Stimulation

Laser-Induced Action Potential-Like Measurements of Cardiomyocytes on Microelectrode Arrays for Increased Predictivity o...

On the usefulness of animals as a model system (part II): Considering benefits within distinct use domains

Project website and logo

Generation of Human Nociceptor-Enriched Sensory Neurons for the Study of Pain-Related Dysfunctions

Optimization of the TeraTox assay for preclinical teratogenicity assessment