ERD

Direct Reprogramming of Human Fetal- and Stem Cell-Derived Glial Progenitor Cells into Midbrain Dopaminergic Neurons

Project: TREAT-PD

Updated at: 27-04-2024

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Project acronym TREAT-PD

In vitro modeling of the human dopaminergic system using spatially arranged ventral midbrain–striatum–cortex assembl...

Project: TREAT-PD

Updated at: 27-04-2024

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Project acronym TREAT-PD

hESC-Derived Dopaminergic Transplants Integrate into Basal Ganglia Circuitry in a Preclinical Model of Parkinson’s Dis...

Project: TREAT-PD

Updated at: 27-04-2024

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Project acronym TREAT-PD

Dual modulation of neuron‐specific microRNAs and the REST complex promotes functional maturation of human adult induce...

Project: TREAT-PD

Updated at: 27-04-2024

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Project acronym TREAT-PD

Impact of α-synuclein pathology on transplanted hESC-derived dopaminergic neurons in a humanized α-synuclein rat model...

Project: TREAT-PD

Updated at: 27-04-2024

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Project acronym TREAT-PD

Single-cell transcriptomics captures features of human midbrain development and dopamine neuron diversity in brain organ...

Project: TREAT-PD

Updated at: 27-04-2024

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Project acronym TREAT-PD

Preclinical quality, safety, and efficacy of a human embryonic stem cell-derived product for the treatment of Parkinson'...

Project: TREAT-PD

Updated at: 27-04-2024

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Project acronym TREAT-PD

Silk scaffolding drives self-assembly of functional and mature human brain organoids

Project: TREAT-PD

Updated at: 27-04-2024

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Project acronym TREAT-PD

Single-cell RNA sequencing reveals midbrain dopamine neuron diversity emerging during mouse brain development

Project: TREAT-PD

Updated at: 27-04-2024

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Project acronym TREAT-PD

Cell‐based therapy for Parkinson's disease: A journey through decades toward the light side of the Force

Project: TREAT-PD

Updated at: 27-04-2024

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Project acronym TREAT-PD

Single-cell transcriptional and functional analysis of dopaminergic neurons in organoid-like cultures derived from human...

Project: TREAT-PD

Updated at: 27-04-2024

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Project acronym TREAT-PD

Single cell transcriptomics identifies stem cell-derived graft composition in a model of Parkinson’s disease

Project: TREAT-PD

Updated at: 27-04-2024

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Project acronym TREAT-PD

From Skin to Brain: A Parkinson’s Disease Patient Transplanted with His Own Cells

Project: TREAT-PD

Updated at: 27-04-2024

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Project acronym TREAT-PD

Periodic Reporting for period 4 - TREAT-PD (Patient-specific treatment for Parkinson's disease using reprogrammed skin c...

Project: TREAT-PD

Updated at: 27-04-2024

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Project acronym TREAT-PD

Grafts Derived from an α-Synuclein Triplication Patient Mediate Functional Recovery but Develop Disease-Associated Path...

Project: TREAT-PD

Updated at: 27-04-2024

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Project acronym TREAT-PD

Modeling neural tube development by differentiation of human embryonic stem cells in a microfluidic WNT gradient

Project: TREAT-PD

Updated at: 27-04-2024

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Project acronym TREAT-PD

Single-Cell Profiling of Coding and Noncoding Genes in Human Dopamine Neuron Differentiation

Project: TREAT-PD

Updated at: 27-04-2024

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Project acronym TREAT-PD

Evaluation of TH-Cre knock-in cell lines for detection and specific targeting of stem cell-derived dopaminergic neurons

Project: TREAT-PD

Updated at: 27-04-2024

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Project acronym TREAT-PD

A novel two-factor monosynaptic TRIO tracing method for assessment of circuit integration of hESC-derived dopamine trans...

Project: TREAT-PD

Updated at: 27-04-2024

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Project acronym TREAT-PD

Transsynaptic tracing and its emerging use to assess graft-reconstructed neural circuits

Project: TREAT-PD

Updated at: 27-04-2024

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Project acronym TREAT-PD

The future of stem cell therapies for Parkinson disease

Project: TREAT-PD

Updated at: 27-04-2024

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Project acronym TREAT-PD

Repairing the Brain: Cell Replacement Using Stem Cell-Based Technologies

Project: TREAT-PD

Updated at: 27-04-2024

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Project acronym TREAT-PD

Generation of Human Ventral Midbrain Organoids Derived from Pluripotent Stem Cells

Project: TREAT-PD

Updated at: 27-04-2024

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Project acronym TREAT-PD

In vivo conversion of dopamine neurons in mouse models of Parkinson’s disease — a future approach for regenerative t...

Project: TREAT-PD

Updated at: 27-04-2024

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Project acronym TREAT-PD

Age-related pathological impairments in directly reprogrammed dopaminergic neurons derived from patients with idiopathic...

Project: TREAT-PD

Updated at: 27-04-2024

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Project acronym TREAT-PD

Deconvolution of spatial sequencing provides accurate characterization of hESC-derived DA transplants in vivo

Project: TREAT-PD

Updated at: 27-04-2024

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Project acronym TREAT-PD

Neuronal Replacement as a Tool for Basal Ganglia Circuitry Repair: 40 Years in Perspective

Project: TREAT-PD

Updated at: 27-04-2024

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Project acronym TREAT-PD

Resources

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Direct Reprogramming of Human Fetal- and Stem Cell-Derived Glial Progenitor Cells into Midbrain Dopaminergic Neurons

In vitro modeling of the human dopaminergic system using spatially arranged ventral midbrain–striatum–cortex assembl...

hESC-Derived Dopaminergic Transplants Integrate into Basal Ganglia Circuitry in a Preclinical Model of Parkinson’s Dis...

Dual modulation of neuron‐specific microRNAs and the REST complex promotes functional maturation of human adult induce...

Impact of α-synuclein pathology on transplanted hESC-derived dopaminergic neurons in a humanized α-synuclein rat model...

Single-cell transcriptomics captures features of human midbrain development and dopamine neuron diversity in brain organ...

Preclinical quality, safety, and efficacy of a human embryonic stem cell-derived product for the treatment of Parkinson'...

Silk scaffolding drives self-assembly of functional and mature human brain organoids

Single-cell RNA sequencing reveals midbrain dopamine neuron diversity emerging during mouse brain development

Cell‐based therapy for Parkinson's disease: A journey through decades toward the light side of the Force

Single-cell transcriptional and functional analysis of dopaminergic neurons in organoid-like cultures derived from human...

Single cell transcriptomics identifies stem cell-derived graft composition in a model of Parkinson’s disease

From Skin to Brain: A Parkinson’s Disease Patient Transplanted with His Own Cells

Periodic Reporting for period 4 - TREAT-PD (Patient-specific treatment for Parkinson's disease using reprogrammed skin c...

Grafts Derived from an α-Synuclein Triplication Patient Mediate Functional Recovery but Develop Disease-Associated Path...

Modeling neural tube development by differentiation of human embryonic stem cells in a microfluidic WNT gradient

Single-Cell Profiling of Coding and Noncoding Genes in Human Dopamine Neuron Differentiation

Evaluation of TH-Cre knock-in cell lines for detection and specific targeting of stem cell-derived dopaminergic neurons

A novel two-factor monosynaptic TRIO tracing method for assessment of circuit integration of hESC-derived dopamine trans...

Transsynaptic tracing and its emerging use to assess graft-reconstructed neural circuits

The future of stem cell therapies for Parkinson disease

Repairing the Brain: Cell Replacement Using Stem Cell-Based Technologies

Generation of Human Ventral Midbrain Organoids Derived from Pluripotent Stem Cells

In vivo conversion of dopamine neurons in mouse models of Parkinson’s disease — a future approach for regenerative t...

Age-related pathological impairments in directly reprogrammed dopaminergic neurons derived from patients with idiopathic...

Deconvolution of spatial sequencing provides accurate characterization of hESC-derived DA transplants in vivo

Neuronal Replacement as a Tool for Basal Ganglia Circuitry Repair: 40 Years in Perspective