ERD

Inflammatory signaling in genomically instable cancers

Project: TENSION

Updated at: 27-04-2024

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RIF1 promotes replication fork protection and efficient restart to maintain genome stability

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Updated at: 27-04-2024

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Cyclin E expression is associated with high levels of replication stress in triple-negative breast cancer

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Updated at: 27-04-2024

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Modeling of Cisplatin-Induced Signaling Dynamics in Triple-Negative Breast Cancer Cells Reveals Mediators of Sensitivity

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Updated at: 27-04-2024

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Improving gene function predictions using independent transcriptional components

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Updated at: 27-04-2024

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BRCA2 deficiency instigates cGAS-mediated inflammatory signaling and confers sensitivity to tumor necrosis factor-alpha-...

Project: TENSION

Updated at: 27-04-2024

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TPX2/Aurora kinase A signaling as a potential therapeutic target in genomically unstable cancer cells

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Updated at: 27-04-2024

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Identification of relevant drugable targets in diffuse large B-cell lymphoma using a genome-wide unbiased CD20 guilt-by ...

Project: TENSION

Updated at: 27-04-2024

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Identification of Two Protein-Signaling States Delineating Transcriptionally Heterogeneous Human Medulloblastoma

Project: TENSION

Updated at: 27-04-2024

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Selective Loss of PARG Restores PARylation and Counteracts PARP Inhibitor-Mediated Synthetic Lethality

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Updated at: 27-04-2024

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Replication stress: Driver and therapeutic target in genomically instable cancers

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Updated at: 27-04-2024

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Never tear us a-PARP: Dealing with DNA lesions during mitosis

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Updated at: 27-04-2024

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Periodic Reporting for period 4 - TENSION (Targeting replication stress recovery pathways in oncology)

Project: TENSION

Updated at: 27-04-2024

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Overexpression of Cyclin E1 or Cdc25A leads to replication stress, mitotic aberrancies, and increased sensitivity to rep...

Project: TENSION

Updated at: 27-04-2024

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Progression through mitosis promotes PARP inhibitor-induced cytotoxicity in homologous recombination-deficient cancer ce...

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Updated at: 27-04-2024

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Transcriptional effects of copy number alterations in a large set of human cancers

Project: TENSION

Updated at: 27-04-2024

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Therapeutic targeting and patient selection for cancers with homologous recombination defects

Project: TENSION

Updated at: 27-04-2024

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Project acronym TENSION

Premature mitotic entry induced by ATR inhibition potentiates olaparib inhibition‐mediated genomic instability, inflam...

Project: TENSION

Updated at: 27-04-2024

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The RECQL helicase prevents replication fork collapse during replication stress

Project: TENSION

Updated at: 27-04-2024

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Deposition Bias of Chromatin Proteins Inverts under DNA Replication Stress Conditions

Project: TENSION

Updated at: 27-04-2024

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Shutting down the power supply for DNA repair in cancer cells

Project: TENSION

Updated at: 27-04-2024

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Project acronym TENSION

Genomic instability, inflammatory signaling and response to cancer immunotherapy.

Project: TENSION

Updated at: 27-04-2024

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Project acronym TENSION

Shaping the BRCAness mutational landscape by alternative double-strand break repair, replication stress and mitotic aber...

Project: TENSION

Updated at: 27-04-2024

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Project acronym TENSION

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Inflammatory signaling in genomically instable cancers

RIF1 promotes replication fork protection and efficient restart to maintain genome stability

Cyclin E expression is associated with high levels of replication stress in triple-negative breast cancer

Modeling of Cisplatin-Induced Signaling Dynamics in Triple-Negative Breast Cancer Cells Reveals Mediators of Sensitivity

Improving gene function predictions using independent transcriptional components

BRCA2 deficiency instigates cGAS-mediated inflammatory signaling and confers sensitivity to tumor necrosis factor-alpha-...

TPX2/Aurora kinase A signaling as a potential therapeutic target in genomically unstable cancer cells

Identification of relevant drugable targets in diffuse large B-cell lymphoma using a genome-wide unbiased CD20 guilt-by ...

Identification of Two Protein-Signaling States Delineating Transcriptionally Heterogeneous Human Medulloblastoma

Selective Loss of PARG Restores PARylation and Counteracts PARP Inhibitor-Mediated Synthetic Lethality

Replication stress: Driver and therapeutic target in genomically instable cancers

Never tear us a-PARP: Dealing with DNA lesions during mitosis

Periodic Reporting for period 4 - TENSION (Targeting replication stress recovery pathways in oncology)

Overexpression of Cyclin E1 or Cdc25A leads to replication stress, mitotic aberrancies, and increased sensitivity to rep...

Progression through mitosis promotes PARP inhibitor-induced cytotoxicity in homologous recombination-deficient cancer ce...

Transcriptional effects of copy number alterations in a large set of human cancers

Therapeutic targeting and patient selection for cancers with homologous recombination defects

Premature mitotic entry induced by ATR inhibition potentiates olaparib inhibition‐mediated genomic instability, inflam...

The RECQL helicase prevents replication fork collapse during replication stress

Deposition Bias of Chromatin Proteins Inverts under DNA Replication Stress Conditions

Shutting down the power supply for DNA repair in cancer cells

Genomic instability, inflammatory signaling and response to cancer immunotherapy.

Shaping the BRCAness mutational landscape by alternative double-strand break repair, replication stress and mitotic aber...