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Personalized whole‐body models integrate metabolism, physiology, and the gut microbiome

Project: BugTheDrug

Updated at: 27-04-2024

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Project acronym BugTheDrug

Microbiome Modelling Toolbox 2.0: efficient, tractable modelling of microbiome communities

Project: BugTheDrug

Updated at: 27-04-2024

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Project acronym BugTheDrug

Systems biology elucidates the distinctive metabolic niche filled by the human gut microbe Eggerthella lenta

Project: BugTheDrug

Updated at: 27-04-2024

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Project acronym BugTheDrug

Preterm birth is associated with xenobiotics and predicted by the vaginal metabolome

Project: BugTheDrug

Updated at: 27-04-2024

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Project acronym BugTheDrug

Genome-Scale Metabolic Modeling of the Human Microbiome in the Era of Personalized Medicine

Project: BugTheDrug

Updated at: 27-04-2024

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Project acronym BugTheDrug

Periodic Reporting for period 3 - BugTheDrug (Predicting the effects of gut microbiota and diet on an individual’s dru...

Project: BugTheDrug

Updated at: 27-04-2024

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Project acronym BugTheDrug

Rare genetic variants affecting urine metabolite levels link population variation to inborn errors of metabolism

Project: BugTheDrug

Updated at: 27-04-2024

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Project acronym BugTheDrug

Comparative Genomic Analysis Reveals Novel Microcompartment-Associated Metabolic Pathways in the Human Gut Microbiome

Project: BugTheDrug

Updated at: 27-04-2024

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Project acronym BugTheDrug

Integration of a physiologically-based pharmacokinetic model with a whole-body, organ-resolved genome-scale model for ch...

Project: BugTheDrug

Updated at: 27-04-2024

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Project acronym BugTheDrug

Integration of constraint-based modeling with fecal metabolomics reveals large deleterious effects of Fusobacterium spp....

Project: BugTheDrug

Updated at: 27-04-2024

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Project acronym BugTheDrug

The Effects of Hospitalisation on the Serum Metabolome in COVID-19 Patients

Project: BugTheDrug

Updated at: 27-04-2024

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Project acronym BugTheDrug

DEMETER: efficient simultaneous curation of genome-scale reconstructions guided by experimental data and refined gene an...

Project: BugTheDrug

Updated at: 27-04-2024

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Project acronym BugTheDrug

Metabolic modelling reveals broad changes in gut microbial metabolism in inflammatory bowel disease patients with dysbio...

Project: BugTheDrug

Updated at: 27-04-2024

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Project acronym BugTheDrug

Cardinality optimization in constraint-based modelling: application to human metabolism

Project: BugTheDrug

Updated at: 27-04-2024

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Integrated In Vitro and In Silico Modeling Delineates the Molecular Effects of a Synbiotic Regimen on Colorectal-Cancer...

Project: BugTheDrug

Updated at: 27-04-2024

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Project acronym BugTheDrug

Integrated Analyses of Microbiome and Longitudinal Metabolome Data Reveal Microbial-Host Interactions on Sulfur Metaboli...

Project: BugTheDrug

Updated at: 27-04-2024

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Project acronym BugTheDrug

Methanogenic granule growth and development is a continual process characterized by distinct morphological features

Project: BugTheDrug

Updated at: 27-04-2024

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Project acronym BugTheDrug

NMR Metabolomics Reveal Urine Markers of Microbiome Diversity and Identify Benzoate Metabolism as a Mediator between Hig...

Project: BugTheDrug

Updated at: 27-04-2024

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Project acronym BugTheDrug

Causal inference on microbiome-metabolome relations in observational host-microbiome data via in silico in vivo associat...

Project: BugTheDrug

Updated at: 27-04-2024

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Project acronym BugTheDrug

The Microbiome Modeling Toolbox: from microbial interactions to personalized microbial communities

Project: BugTheDrug

Updated at: 27-04-2024

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Project acronym BugTheDrug

Genome-scale metabolic reconstruction of 7,302 human microorganisms for personalized medicine

Project: BugTheDrug

Updated at: 27-04-2024

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Project acronym BugTheDrug

MetaboAnnotator: an efficient toolbox to annotate metabolites in genome-scale metabolic reconstructions

Project: BugTheDrug

Updated at: 27-04-2024

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Project acronym BugTheDrug

Whole-body metabolic modelling predicts isoleucine dependency of SARS-CoV-2 replication

Project: BugTheDrug

Updated at: 27-04-2024

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Project acronym BugTheDrug

Systematic assessment of secondary bile acid metabolism in gut microbes reveals distinct metabolic capabilities in infla...

Project: BugTheDrug

Updated at: 27-04-2024

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Project acronym BugTheDrug

The Virtual Metabolic Human database: integrating human and gut microbiome metabolism with nutrition and disease

Project: BugTheDrug

Updated at: 27-04-2024

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Project acronym BugTheDrug

Predicting gastrointestinal drug effects using contextualized metabolic models

Project: BugTheDrug

Updated at: 27-04-2024

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Project acronym BugTheDrug

The gut microbial metabolite formate exacerbates colorectal cancer progression

Project: BugTheDrug

Updated at: 27-04-2024

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Project acronym BugTheDrug

A nutrition algorithm to optimize feed and medium composition using genome-scale metabolic models

Project: BugTheDrug

Updated at: 27-04-2024

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Project acronym BugTheDrug

Dynamic flux balance analysis of whole-body metabolism for type 1 diabetes

Project: BugTheDrug

Updated at: 27-04-2024

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Advances in constraint-based modelling of microbial communities

Project: BugTheDrug

Updated at: 27-04-2024

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Project acronym BugTheDrug

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Personalized whole‐body models integrate metabolism, physiology, and the gut microbiome

Microbiome Modelling Toolbox 2.0: efficient, tractable modelling of microbiome communities

Systems biology elucidates the distinctive metabolic niche filled by the human gut microbe Eggerthella lenta

Preterm birth is associated with xenobiotics and predicted by the vaginal metabolome

Genome-Scale Metabolic Modeling of the Human Microbiome in the Era of Personalized Medicine

Periodic Reporting for period 3 - BugTheDrug (Predicting the effects of gut microbiota and diet on an individual’s dru...

Rare genetic variants affecting urine metabolite levels link population variation to inborn errors of metabolism

Comparative Genomic Analysis Reveals Novel Microcompartment-Associated Metabolic Pathways in the Human Gut Microbiome

Integration of a physiologically-based pharmacokinetic model with a whole-body, organ-resolved genome-scale model for ch...

Integration of constraint-based modeling with fecal metabolomics reveals large deleterious effects of Fusobacterium spp....

The Effects of Hospitalisation on the Serum Metabolome in COVID-19 Patients

DEMETER: efficient simultaneous curation of genome-scale reconstructions guided by experimental data and refined gene an...

Metabolic modelling reveals broad changes in gut microbial metabolism in inflammatory bowel disease patients with dysbio...

Cardinality optimization in constraint-based modelling: application to human metabolism

Integrated In Vitro and In Silico Modeling Delineates the Molecular Effects of a Synbiotic Regimen on Colorectal-Cancer...

Integrated Analyses of Microbiome and Longitudinal Metabolome Data Reveal Microbial-Host Interactions on Sulfur Metaboli...

Methanogenic granule growth and development is a continual process characterized by distinct morphological features

NMR Metabolomics Reveal Urine Markers of Microbiome Diversity and Identify Benzoate Metabolism as a Mediator between Hig...

Causal inference on microbiome-metabolome relations in observational host-microbiome data via in silico in vivo associat...

The Microbiome Modeling Toolbox: from microbial interactions to personalized microbial communities

Genome-scale metabolic reconstruction of 7,302 human microorganisms for personalized medicine

MetaboAnnotator: an efficient toolbox to annotate metabolites in genome-scale metabolic reconstructions

Whole-body metabolic modelling predicts isoleucine dependency of SARS-CoV-2 replication

Systematic assessment of secondary bile acid metabolism in gut microbes reveals distinct metabolic capabilities in infla...

The Virtual Metabolic Human database: integrating human and gut microbiome metabolism with nutrition and disease

Predicting gastrointestinal drug effects using contextualized metabolic models

The gut microbial metabolite formate exacerbates colorectal cancer progression

A nutrition algorithm to optimize feed and medium composition using genome-scale metabolic models

Dynamic flux balance analysis of whole-body metabolism for type 1 diabetes

Advances in constraint-based modelling of microbial communities