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An anti‐siglec‐8 antibody depletes sputum eosinophils from asthmatic subjects and inhibits lung mast cells

Project: ASTHMACRYSTALCLEAR

Updated at: 27-04-2024

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Project acronym ASTHMACRYSTALCLEAR

Osteopontin Promotes Protective Antigenic Tolerance against Experimental Allergic Airway Disease

Project: ASTHMACRYSTALCLEAR

Updated at: 27-04-2024

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Project acronym ASTHMACRYSTALCLEAR

Human Lung Conventional Dendritic Cells Orchestrate Lymphoid Neogenesis during Chronic Obstructive Pulmonary Disease

Project: ASTHMACRYSTALCLEAR

Updated at: 27-04-2024

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Project acronym ASTHMACRYSTALCLEAR

Eicosanoid Control Over Antigen Presenting Cells in Asthma

Project: ASTHMACRYSTALCLEAR

Updated at: 27-04-2024

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TAO-kinase 3 governs the terminal differentiation of NOTCH2-dependent splenic conventional dendritic cells

Project: ASTHMACRYSTALCLEAR

Updated at: 27-04-2024

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Tnfaip3 expression in pulmonary conventional type 1 Langerin‐expressing dendritic cells regulates T helper 2‐mediate...

Project: ASTHMACRYSTALCLEAR

Updated at: 27-04-2024

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Charcot-Leyden crystals promote neutrophilic inflammation in patients with nasal polyposis

Project: ASTHMACRYSTALCLEAR

Updated at: 27-04-2024

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Protein crystallization promotes type 2 immunity and is reversible by antibody treatment

Project: ASTHMACRYSTALCLEAR

Updated at: 27-04-2024

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Characterization of a lung epithelium specific E-cadherin knock-out model: Implications for obstructive lung pathology

Project: ASTHMACRYSTALCLEAR

Updated at: 27-04-2024

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Periodic Reporting for period 2 - ASTHMACRYSTALCLEAR (Role of protein crystallization in type 2 immunity and asthma)

Project: ASTHMACRYSTALCLEAR

Updated at: 27-04-2024

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Professional and ‘Amateur’ Antigen-Presenting Cells In Type 2 Immunity

Project: ASTHMACRYSTALCLEAR

Updated at: 27-04-2024

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CCR2- and Flt3-Dependent Inflammatory Conventional Type 2 Dendritic Cells Are Necessary for the Induction of Adaptive Im...

Project: ASTHMACRYSTALCLEAR

Updated at: 27-04-2024

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Project acronym ASTHMACRYSTALCLEAR

Personalized medicine with biologics for severe type 2 asthma: current status and future prospects

Project: ASTHMACRYSTALCLEAR

Updated at: 27-04-2024

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Project acronym ASTHMACRYSTALCLEAR

Prophylactic allergen immunotherapy with Der p 2 prevents murine asthma by regulating lung GM-CSF

Project: ASTHMACRYSTALCLEAR

Updated at: 27-04-2024

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IL-33trap is a novel IL-33–neutralizing biologic that inhibits allergic airway inflammation

Project: ASTHMACRYSTALCLEAR

Updated at: 27-04-2024

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Project acronym ASTHMACRYSTALCLEAR

Co-Activation of Glucocorticoid Receptor and Peroxisome Proliferator–Activated Receptor-γ in Murine Skin Prevents Wor...

Project: ASTHMACRYSTALCLEAR

Updated at: 27-04-2024

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Project acronym ASTHMACRYSTALCLEAR

Isolated Schistosoma mansoni eggs prevent allergic airway inflammation

Project: ASTHMACRYSTALCLEAR

Updated at: 27-04-2024

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A pathophysiological role of PDE3 in allergic airway inflammation

Project: ASTHMACRYSTALCLEAR

Updated at: 27-04-2024

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Project acronym ASTHMACRYSTALCLEAR

The hygiene hypothesis: immunological mechanisms of airway tolerance

Project: ASTHMACRYSTALCLEAR

Updated at: 27-04-2024

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Project acronym ASTHMACRYSTALCLEAR

Wnt and Hippo pathways in regulatory T cells: a NOTCH above in asthma

Project: ASTHMACRYSTALCLEAR

Updated at: 27-04-2024

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How a farming environment protects from atopy

Project: ASTHMACRYSTALCLEAR

Updated at: 27-04-2024

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Inflammatory Type 2 cDCs Acquire Features of cDC1s and Macrophages to Orchestrate Immunity to Respiratory Virus Infectio...

Project: ASTHMACRYSTALCLEAR

Updated at: 27-04-2024

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Project acronym ASTHMACRYSTALCLEAR

Local immune response to food antigens drives meal-induced abdominal pain

Project: ASTHMACRYSTALCLEAR

Updated at: 27-04-2024

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Epithelial dysregulation in obese severe asthmatics with gastro-oesophageal reflux

Project: ASTHMACRYSTALCLEAR

Updated at: 27-04-2024

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The ORMDL3 asthma susceptibility gene regulates systemic ceramide levels without altering key asthma features in mice

Project: ASTHMACRYSTALCLEAR

Updated at: 27-04-2024

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A bispecific antibody strategy to target multiple type 2 cytokines in asthma

Project: ASTHMACRYSTALCLEAR

Updated at: 27-04-2024

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Project acronym ASTHMACRYSTALCLEAR

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An anti‐siglec‐8 antibody depletes sputum eosinophils from asthmatic subjects and inhibits lung mast cells

Osteopontin Promotes Protective Antigenic Tolerance against Experimental Allergic Airway Disease

Human Lung Conventional Dendritic Cells Orchestrate Lymphoid Neogenesis during Chronic Obstructive Pulmonary Disease

Eicosanoid Control Over Antigen Presenting Cells in Asthma

TAO-kinase 3 governs the terminal differentiation of NOTCH2-dependent splenic conventional dendritic cells

Tnfaip3 expression in pulmonary conventional type 1 Langerin‐expressing dendritic cells regulates T helper 2‐mediate...

Charcot-Leyden crystals promote neutrophilic inflammation in patients with nasal polyposis

Protein crystallization promotes type 2 immunity and is reversible by antibody treatment

Characterization of a lung epithelium specific E-cadherin knock-out model: Implications for obstructive lung pathology

Periodic Reporting for period 2 - ASTHMACRYSTALCLEAR (Role of protein crystallization in type 2 immunity and asthma)

Professional and ‘Amateur’ Antigen-Presenting Cells In Type 2 Immunity

CCR2- and Flt3-Dependent Inflammatory Conventional Type 2 Dendritic Cells Are Necessary for the Induction of Adaptive Im...

Personalized medicine with biologics for severe type 2 asthma: current status and future prospects

Prophylactic allergen immunotherapy with Der p 2 prevents murine asthma by regulating lung GM-CSF

IL-33trap is a novel IL-33–neutralizing biologic that inhibits allergic airway inflammation

Co-Activation of Glucocorticoid Receptor and Peroxisome Proliferator–Activated Receptor-γ in Murine Skin Prevents Wor...

Isolated Schistosoma mansoni eggs prevent allergic airway inflammation

A pathophysiological role of PDE3 in allergic airway inflammation

The hygiene hypothesis: immunological mechanisms of airway tolerance

Wnt and Hippo pathways in regulatory T cells: a NOTCH above in asthma

How a farming environment protects from atopy

Inflammatory Type 2 cDCs Acquire Features of cDC1s and Macrophages to Orchestrate Immunity to Respiratory Virus Infectio...

Local immune response to food antigens drives meal-induced abdominal pain

Epithelial dysregulation in obese severe asthmatics with gastro-oesophageal reflux

The ORMDL3 asthma susceptibility gene regulates systemic ceramide levels without altering key asthma features in mice

A bispecific antibody strategy to target multiple type 2 cytokines in asthma