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Gut microbiota severely hampers the efficacy of NAD-lowering therapy in leukemia.

Project: INTEGRATA

Updated at: 28-04-2024

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Structure-Based Identification and Biological Characterization of New NAPRT Inhibitors

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Immune Response Dysfunction in Chronic Lymphocytic Leukemia: Dissecting Molecular Mechanisms and Microenvironmental Cond...

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Updated at: 28-04-2024

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Ranking

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NUDT22 promotes cancer growth through pyrimidine salvage

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Updated at: 28-04-2024

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SSC activities

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Updated at: 28-04-2024

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Dendritic cells direct circadian anti-tumour immune responses

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Updated at: 28-04-2024

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Development of Small Molecule NUDT22 Inhibitors for Uses in Cancer

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Updated at: 28-04-2024

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Periodic Reporting for period 2 - INTEGRATA (Integrating chemical and biological approaches to target NAD production and...

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Updated at: 28-04-2024

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Sirtuin 6 inhibition protects against glucocorticoid-induced skeletal muscle atrophy by regulating IGF/PI3K/AKT signalin...

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Updated at: 28-04-2024

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Targeting of the A2A adenosine receptor counteracts immunosuppression in vivo in a mouse model of chronic lymphocytic le...

Project: INTEGRATA

Updated at: 28-04-2024

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Virtual Screening in the Identification of Sirtuins' Activity Modulators

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Updated at: 28-04-2024

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Iminosugar-Based Nicotinamide Phosphoribosyltransferase (NAMPT) Inhibitors as Potential Anti-Pancreatic Cancer Agents

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Updated at: 28-04-2024

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Iminosugars as glycosyltransferase inhibitors

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Call publication

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Scientific meetings

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PhD thesis

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Supervisory Board of the network

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Updated at: 28-04-2024

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Final Workshop

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Updated at: 28-04-2024

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Mitochondrial rewiring drives metabolic adaptation to NAD(H) shortage in triple negative breast cancer cells

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Updated at: 28-04-2024

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Local training

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Updated at: 28-04-2024

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Individual CDP

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Updated at: 28-04-2024

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Anticancer Activities of Novel Nicotinamide Phosphoribosyltransferase Inhibitors in Hematological Malignancies

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Updated at: 28-04-2024

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Synthesis and structure-activity relationship of new nicotinamide phosphoribosyltransferase inhibitors with antitumor ac...

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Updated at: 28-04-2024

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Loss of p53 activates thyroid hormone via type 2 deiodinase and enhances DNA damage

Project: INTEGRATA

Updated at: 28-04-2024

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Identification of NAPRT Inhibitors with Anti-Cancer Properties by In Silico Drug Discovery

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Updated at: 28-04-2024

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Project acronym INTEGRATA

Advances in NAD-Lowering Agents for Cancer Treatment

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Updated at: 28-04-2024

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Re-Discovery of Pyrimidine Salvage as Target in Cancer Therapy

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Updated at: 28-04-2024

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Secondments

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Updated at: 28-04-2024

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Gut microbiota severely hampers the efficacy of NAD-lowering therapy in leukemia.

Structure-Based Identification and Biological Characterization of New NAPRT Inhibitors

Website

Immune Response Dysfunction in Chronic Lymphocytic Leukemia: Dissecting Molecular Mechanisms and Microenvironmental Cond...

Ranking

NUDT22 promotes cancer growth through pyrimidine salvage

SSC activities

Dendritic cells direct circadian anti-tumour immune responses

Development of Small Molecule NUDT22 Inhibitors for Uses in Cancer

Periodic Reporting for period 2 - INTEGRATA (Integrating chemical and biological approaches to target NAD production and...

Sirtuin 6 inhibition protects against glucocorticoid-induced skeletal muscle atrophy by regulating IGF/PI3K/AKT signalin...

Targeting of the A2A adenosine receptor counteracts immunosuppression in vivo in a mouse model of chronic lymphocytic le...

Virtual Screening in the Identification of Sirtuins' Activity Modulators

Iminosugar-Based Nicotinamide Phosphoribosyltransferase (NAMPT) Inhibitors as Potential Anti-Pancreatic Cancer Agents

Iminosugars as glycosyltransferase inhibitors

Call publication

Scientific meetings

PhD thesis

Supervisory Board of the network

Final Workshop

Mitochondrial rewiring drives metabolic adaptation to NAD(H) shortage in triple negative breast cancer cells

Local training

Individual CDP

Anticancer Activities of Novel Nicotinamide Phosphoribosyltransferase Inhibitors in Hematological Malignancies

Synthesis and structure-activity relationship of new nicotinamide phosphoribosyltransferase inhibitors with antitumor ac...

Loss of p53 activates thyroid hormone via type 2 deiodinase and enhances DNA damage

Identification of NAPRT Inhibitors with Anti-Cancer Properties by In Silico Drug Discovery

Advances in NAD-Lowering Agents for Cancer Treatment

Re-Discovery of Pyrimidine Salvage as Target in Cancer Therapy

Secondments