ERD

Periodic Reporting for period 2 - OXYTRAIN (Harnessing the power of enzymatic oxygen activation)

Project: OXYTRAIN

Updated at: 28-04-2024

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Project acronym OXYTRAIN

Characterization of a thermostable flavin-containing monooxygenase from Nitrincola lacisaponensis (NiFMO)

Project: OXYTRAIN

Updated at: 28-04-2024

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Project acronym OXYTRAIN

P450 Monooxygenases Enable Rapid Late-Stage Diversification of Natural Products via C−H Bond Activation

Project: OXYTRAIN

Updated at: 28-04-2024

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Project acronym OXYTRAIN

Conference organisation

Project: OXYTRAIN

Updated at: 28-04-2024

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Project acronym OXYTRAIN

Identification of substrates and inhibitors of HPP oxygenase

Project: OXYTRAIN

Updated at: 28-04-2024

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Project acronym OXYTRAIN

Ancestral-sequence reconstruction unveils the structural basis of function in mammalian FMOs

Project: OXYTRAIN

Updated at: 28-04-2024

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Project acronym OXYTRAIN

Current state and future perspectives of engineered and artificial peroxygenases for the oxyfunctionalization of organic...

Project: OXYTRAIN

Updated at: 28-04-2024

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Project acronym OXYTRAIN

Evaluation of engineered flavin-dependent monooxygenases in industrial settings

Project: OXYTRAIN

Updated at: 28-04-2024

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Project acronym OXYTRAIN

PQS-cleaving cofactor-independent dioxygenases purified and functionally characterised

Project: OXYTRAIN

Updated at: 28-04-2024

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Project acronym OXYTRAIN

Project Website

Project: OXYTRAIN

Updated at: 28-04-2024

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Project acronym OXYTRAIN

Identification of improved flavin-dependent monooxygenases

Project: OXYTRAIN

Updated at: 28-04-2024

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Project acronym OXYTRAIN

A SERS-based method for the assaying of LPMO activity on a range of polysaccharide substrates

Project: OXYTRAIN

Updated at: 28-04-2024

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Project acronym OXYTRAIN

A range of new small-molecule copper complexes which can mimic LPMOs

Project: OXYTRAIN

Updated at: 28-04-2024

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Project acronym OXYTRAIN

Libraries of enzyme mutants prepared

Project: OXYTRAIN

Updated at: 28-04-2024

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Project acronym OXYTRAIN

Crystal structures of flavin-dependent monooxygenases

Project: OXYTRAIN

Updated at: 28-04-2024

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Project acronym OXYTRAIN

Identification of amino acid positions that govern selectivity of three heme-dependent monooxygenases

Project: OXYTRAIN

Updated at: 28-04-2024

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Project acronym OXYTRAIN

Identification of at least 2, preferably 5 new hydroxylating heme-dependent monooxygenases

Project: OXYTRAIN

Updated at: 28-04-2024

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Project acronym OXYTRAIN

Protocol for evaluating (improved) monooxygenases for industrially relevant conversions

Project: OXYTRAIN

Updated at: 28-04-2024

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Project acronym OXYTRAIN

Three simultaneous saturation mutagenesis libraries per monooxygenase

Project: OXYTRAIN

Updated at: 28-04-2024

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Project acronym OXYTRAIN

Awards of doctoral degrees

Project: OXYTRAIN

Updated at: 28-04-2024

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Project acronym OXYTRAIN

Characterization of an AA9 LPMO from Thielavia australiensis, TausLPMO9B, under industrially relevant lignocellulose sac...

Project: OXYTRAIN

Updated at: 28-04-2024

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Project acronym OXYTRAIN

Ancestral reconstruction of mammalian FMO1 enables structural determination, revealing unique features that explain its ...

Project: OXYTRAIN

Updated at: 28-04-2024

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Project acronym OXYTRAIN

Mechanistic basis of substrate–O 2 coupling within a chitin-active lytic polysaccharide monooxygenase: An integrated N...

Project: OXYTRAIN

Updated at: 28-04-2024

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Project acronym OXYTRAIN

Directed Evolution of P450 BM3 towards Functionalization of Aromatic O-Heterocycles

Project: OXYTRAIN

Updated at: 28-04-2024

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Project acronym OXYTRAIN

An α/β-Hydrolase Fold Subfamily Comprising Pseudomonas Quinolone Signal-Cleaving Dioxygenases

Project: OXYTRAIN

Updated at: 28-04-2024

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Project acronym OXYTRAIN

Flavin-dependent monooxygenases produced and purified

Project: OXYTRAIN

Updated at: 28-04-2024

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Project acronym OXYTRAIN

Isolated and characterised hydroxylated heterocycles in multi mg to g scale

Project: OXYTRAIN

Updated at: 28-04-2024

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Project acronym OXYTRAIN

Generation and transfer of six SSB mutant libraries to the RWTH/TUG partners for screening

Project: OXYTRAIN

Updated at: 28-04-2024

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Project acronym OXYTRAIN

High-resolution crystal structures of HPP oxygenase complexed with substrate or inhibitors

Project: OXYTRAIN

Updated at: 28-04-2024

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Project acronym OXYTRAIN

Cofactor-independent oxygenases with few new functions identified within the tautomerase superfamily

Project: OXYTRAIN

Updated at: 28-04-2024

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Project acronym OXYTRAIN

Resources

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Periodic Reporting for period 2 - OXYTRAIN (Harnessing the power of enzymatic oxygen activation)

Characterization of a thermostable flavin-containing monooxygenase from Nitrincola lacisaponensis (NiFMO)

P450 Monooxygenases Enable Rapid Late-Stage Diversification of Natural Products via C−H Bond Activation

Conference organisation

Identification of substrates and inhibitors of HPP oxygenase

Ancestral-sequence reconstruction unveils the structural basis of function in mammalian FMOs

Current state and future perspectives of engineered and artificial peroxygenases for the oxyfunctionalization of organic...

Evaluation of engineered flavin-dependent monooxygenases in industrial settings

PQS-cleaving cofactor-independent dioxygenases purified and functionally characterised

Project Website

Identification of improved flavin-dependent monooxygenases

A SERS-based method for the assaying of LPMO activity on a range of polysaccharide substrates

A range of new small-molecule copper complexes which can mimic LPMOs

Libraries of enzyme mutants prepared

Crystal structures of flavin-dependent monooxygenases

Identification of amino acid positions that govern selectivity of three heme-dependent monooxygenases

Identification of at least 2, preferably 5 new hydroxylating heme-dependent monooxygenases

Protocol for evaluating (improved) monooxygenases for industrially relevant conversions

Three simultaneous saturation mutagenesis libraries per monooxygenase

Awards of doctoral degrees

Characterization of an AA9 LPMO from Thielavia australiensis, TausLPMO9B, under industrially relevant lignocellulose sac...

Ancestral reconstruction of mammalian FMO1 enables structural determination, revealing unique features that explain its ...

Mechanistic basis of substrate–O 2 coupling within a chitin-active lytic polysaccharide monooxygenase: An integrated N...

Directed Evolution of P450 BM3 towards Functionalization of Aromatic O-Heterocycles

An α/β-Hydrolase Fold Subfamily Comprising Pseudomonas Quinolone Signal-Cleaving Dioxygenases

Flavin-dependent monooxygenases produced and purified

Isolated and characterised hydroxylated heterocycles in multi mg to g scale

Generation and transfer of six SSB mutant libraries to the RWTH/TUG partners for screening

High-resolution crystal structures of HPP oxygenase complexed with substrate or inhibitors

Cofactor-independent oxygenases with few new functions identified within the tautomerase superfamily