ERD

Creation of Facebook & Twitter accounts

Project: INSPIRED

Updated at: 28-04-2024

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Project acronym INSPIRED

Emerging Roles of the Endoplasmic Reticulum Associated Unfolded Protein Response in Cancer Cell Migration and Invasion

Project: INSPIRED

Updated at: 28-04-2024

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Project acronym INSPIRED

Genotoxic stress triggers the activation of IRE1α-dependent RNA decay to modulate the DNA damage response

Project: INSPIRED

Updated at: 28-04-2024

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Project acronym INSPIRED

Molecular modeling provides a structural basis for PERK inhibitor selectivity towards RIPK1

Project: INSPIRED

Updated at: 28-04-2024

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Project acronym INSPIRED

CD90/Thy-1, a Cancer-Associated Cell Surface Signaling Molecule

Project: INSPIRED

Updated at: 28-04-2024

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Project acronym INSPIRED

Role of the early secretory pathway in SARS-CoV-2 infection

Project: INSPIRED

Updated at: 28-04-2024

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Project acronym INSPIRED

Consortium web site established

Project: INSPIRED

Updated at: 28-04-2024

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Project acronym INSPIRED

Dual IRE1 RNase functions dictate glioblastoma development

Project: INSPIRED

Updated at: 28-04-2024

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Project acronym INSPIRED

Inhibition of IRE1 RNase activity modulates the tumor cell secretome and enhances response to chemotherapy

Project: INSPIRED

Updated at: 28-04-2024

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Project acronym INSPIRED

Interactome Screening Identifies the ER Luminal Chaperone Hsp47 as a Regulator of the Unfolded Protein Response Transduc...

Project: INSPIRED

Updated at: 28-04-2024

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Project acronym INSPIRED

Endoplasmic reticulum stress signalling - from basic mechanisms to clinical applications

Project: INSPIRED

Updated at: 28-04-2024

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Project acronym INSPIRED

BCL-2 family: integrating stress responses at the ER to control cell demise

Project: INSPIRED

Updated at: 28-04-2024

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Project acronym INSPIRED

Drug repurposing to target proteostasis and prevent neurodegeneration: accelerating translational efforts

Project: INSPIRED

Updated at: 28-04-2024

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Project acronym INSPIRED

The Unfolded Protein Response: At the Intersection between Endoplasmic Reticulum Function and Mitochondrial Bioenergetic...

Project: INSPIRED

Updated at: 28-04-2024

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Project acronym INSPIRED

Fine-Tuning ER Stress Signal Transducers to Treat Amyotrophic Lateral Sclerosis

Project: INSPIRED

Updated at: 28-04-2024

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Project acronym INSPIRED

The Unfolded Protein Response and Cell Fate Control

Project: INSPIRED

Updated at: 28-04-2024

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Project acronym INSPIRED

Regulation of tumor-stroma interactions by the unfolded protein response

Project: INSPIRED

Updated at: 28-04-2024

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Project acronym INSPIRED

The necroptosis machinery mediates axonal degeneration in a model of Parkinson disease

Project: INSPIRED

Updated at: 28-04-2024

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Project acronym INSPIRED

IRE1α governs cytoskeleton remodelling and cell migration through a direct interaction with filamin A

Project: INSPIRED

Updated at: 28-04-2024

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Project acronym INSPIRED

Disulfide cross-linked multimers of TDP-43 and spinal motoneuron loss in a TDP-43A315T ALS/FTD mouse model

Project: INSPIRED

Updated at: 28-04-2024

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Project acronym INSPIRED

A guide to assessing endoplasmic reticulum homeostasis and stress in mammalian systems

Project: INSPIRED

Updated at: 28-04-2024

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Project acronym INSPIRED

The Unfolded Protein Response in Breast Cancer

Project: INSPIRED

Updated at: 28-04-2024

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Project acronym INSPIRED

Peptidomimetic‐based identification of FDA‐approved compounds inhibiting IRE1 activity

Project: INSPIRED

Updated at: 28-04-2024

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Project acronym INSPIRED

The p75NTR neurotrophin receptor is required to organize the mature neuromuscular synapse by regulating synaptic vesicle...

Project: INSPIRED

Updated at: 28-04-2024

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Project acronym INSPIRED

The UPRosome – decoding novel biological outputs of IRE1α function

Project: INSPIRED

Updated at: 28-04-2024

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Project acronym INSPIRED

Pharmacological Targeting of IRE1 in Cancer

Project: INSPIRED

Updated at: 28-04-2024

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Project acronym INSPIRED

Tumour Cell Secretome in Chemoresistance and Tumour Recurrence

Project: INSPIRED

Updated at: 28-04-2024

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Project acronym INSPIRED

New insights on human IRE1 tetramer structures based on molecular modeling

Project: INSPIRED

Updated at: 28-04-2024

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Project acronym INSPIRED

When Endoplasmic Reticulum Proteostasis Meets the DNA Damage Response

Project: INSPIRED

Updated at: 28-04-2024

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Project acronym INSPIRED

Deciphering the selectivity of inhibitor MKC9989 towards residue K907 in IRE1α; a multiscale in silico approach

Project: INSPIRED

Updated at: 28-04-2024

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Project acronym INSPIRED

Resources

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Creation of Facebook & Twitter accounts

Emerging Roles of the Endoplasmic Reticulum Associated Unfolded Protein Response in Cancer Cell Migration and Invasion

Genotoxic stress triggers the activation of IRE1α-dependent RNA decay to modulate the DNA damage response

Molecular modeling provides a structural basis for PERK inhibitor selectivity towards RIPK1

CD90/Thy-1, a Cancer-Associated Cell Surface Signaling Molecule

Role of the early secretory pathway in SARS-CoV-2 infection

Consortium web site established

Dual IRE1 RNase functions dictate glioblastoma development

Inhibition of IRE1 RNase activity modulates the tumor cell secretome and enhances response to chemotherapy

Interactome Screening Identifies the ER Luminal Chaperone Hsp47 as a Regulator of the Unfolded Protein Response Transduc...

Endoplasmic reticulum stress signalling - from basic mechanisms to clinical applications

BCL-2 family: integrating stress responses at the ER to control cell demise

Drug repurposing to target proteostasis and prevent neurodegeneration: accelerating translational efforts

The Unfolded Protein Response: At the Intersection between Endoplasmic Reticulum Function and Mitochondrial Bioenergetic...

Fine-Tuning ER Stress Signal Transducers to Treat Amyotrophic Lateral Sclerosis

The Unfolded Protein Response and Cell Fate Control

Regulation of tumor-stroma interactions by the unfolded protein response

The necroptosis machinery mediates axonal degeneration in a model of Parkinson disease

IRE1α governs cytoskeleton remodelling and cell migration through a direct interaction with filamin A

Disulfide cross-linked multimers of TDP-43 and spinal motoneuron loss in a TDP-43A315T ALS/FTD mouse model

A guide to assessing endoplasmic reticulum homeostasis and stress in mammalian systems

The Unfolded Protein Response in Breast Cancer

Peptidomimetic‐based identification of FDA‐approved compounds inhibiting IRE1 activity

The p75NTR neurotrophin receptor is required to organize the mature neuromuscular synapse by regulating synaptic vesicle...

The UPRosome – decoding novel biological outputs of IRE1α function

Pharmacological Targeting of IRE1 in Cancer

Tumour Cell Secretome in Chemoresistance and Tumour Recurrence

New insights on human IRE1 tetramer structures based on molecular modeling

When Endoplasmic Reticulum Proteostasis Meets the DNA Damage Response

Deciphering the selectivity of inhibitor MKC9989 towards residue K907 in IRE1α; a multiscale in silico approach